FDPS antibody (N-Term)

Catalog No. ABIN952387

This Rabbit Polyclonal antibody specifically detects FDPS in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for FDPS antibody (N-Term) (ABIN952387)

Target: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FDPS antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-FDPS Antibody

Binding Specificity: AA 53-82, N-Term

Specificity: This antibody reacts to FDPS.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 53-82 amino acids from the N-terminal region of human FDPS

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FDPS

Target: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Alternative Name: FPP Synthetase

Background: This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: FDPS, FPS, Farnesyl diphosphate synthase, Farnesyl pyrophosphate synthetase, KIAA1293

Molecular Weight: 48275 Da

Gene ID: 2224

NCBI Accession: NP_001129293

Pathways: Regulation of Muscle Cell Differentiation