MAML1 antibody (Middle Region)

Catalog No. ABIN953326

This Rabbit Polyclonal antibody specifically detects MAML1 in WB, FACS and EIA. It exhibits reactivity toward Human.

Quick Overview for MAML1 antibody (Middle Region) (ABIN953326)

Target: MAML1 (Mastermind-Like 1 (MAML1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAML1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Product Details anti-MAML1 Antibody

Binding Specificity: AA 205-234, Middle Region

Specificity: This antibody recognizes Human Mastermind-Like Protein 1 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 205-234 amino acids from the Central region of human Mastermind-Like Protein 1 Genename: MAML1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MAML1

Target: MAML1 (Mastermind-Like 1 (MAML1))

Alternative Name: Mastermind-Like Protein 1

Background: This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.Synonyms: MAML1, Mam-1

Molecular Weight: 108054 Da

Gene ID: 9794

NCBI Accession: NP_055572

Pathways: Notch Signaling, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development