MED25 antibody (N-Term)

Catalog No. ABIN953372

The Rabbit Polyclonal anti-MED25 antibody has been validated for WB, IHC (p) and EIA. It is suitable to detect MED25 in samples from Human and Mouse.

Quick Overview for MED25 antibody (N-Term) (ABIN953372)

Target: MED25 (Mediator Complex Subunit 25 (MED25))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED25 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-MED25 Antibody

Binding Specificity: AA 119-148, N-Term

Specificity: This antibody recognizes Human and Mouse MED25 (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 119-148 amino acids from the N-terminal region of human MED25.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MED25

Target: MED25 (Mediator Complex Subunit 25 (MED25))

Alternative Name: MED25

Background: This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2. [provided by RefSeq].Synonyms: ACID1, ARC92, Mediator of RNA polymerase II transcription subunit 25, PTOV2

Molecular Weight: 78171 Da

Gene ID: 81857

NCBI Accession: NP_112235

Pathways: Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response