MED8 antibody (Middle Region)

Catalog No. ABIN953379

The Rabbit Polyclonal anti-MED8 antibody (ABIN953379) specifically detects MED8 in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for MED8 antibody (Middle Region) (ABIN953379)

Target: MED8 (Mediator Complex Subunit 8 (MED8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED8 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-MED8 Antibody

Binding Specificity: AA 102-130, Middle Region

Specificity: This antibody recognizes Human MED8 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 102-130 amino acids from the Central region of human MED8

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MED8

Target: MED8 (Mediator Complex Subunit 8 (MED8))

Alternative Name: MED8

Background: This gene encodes a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. The product of this gene also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase. Two alternative transcripts encoding different isoforms have been described.Synonyms: Activator-recruited cofactor 32 kDa component, Mediator complex 8, Mediator of RNA polymerase II transcription subunit 8

Molecular Weight: 29080 Da

Gene ID: 112950

NCBI Accession: NP_443109

Pathways: Regulation of Lipid Metabolism by PPARalpha