NEIL1 antibody (Middle Region)

Catalog No. ABIN953643

Product Details anti-NEIL1 Antibody

Target: NEIL1 (Endonuclease VIII-Like 1 (NEIL1))

Binding Specificity: AA 137-167, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEIL1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human NEIL1 (Center).

Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide between 137~167 amino acids from the Central region of human NEIL1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for NEIL1

Target: NEIL1 (Endonuclease VIII-Like 1 (NEIL1))

Alternative Name: NEIL1 (NEIL1 Products)

Background: NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).Synonyms: DNA glycosylase/AP lyase Neil1, DNA-(apurinic or apyrimidinic site) lyase Neil1, Endonuclease VIII-like 1, FPG1, NEH1

Molecular Weight: 43684 Da

Gene ID: 79661

NCBI Accession: NP_078884

Pathways: DNA Damage Repair