PALB2 antibody (Middle Region)

Catalog No. ABIN953981

The Rabbit Polyclonal anti-PALB2 antibody has been validated for WB, FACS and EIA. It is suitable to detect PALB2 in samples from Human.

Quick Overview for PALB2 antibody (Middle Region) (ABIN953981)

Target: PALB2 (Partner and Localizer of BRCA2 (PALB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PALB2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Product Details anti-PALB2 Antibody

Binding Specificity: AA 553-582, Middle Region

Specificity: This antibody recognizes Human PALB2 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 553-582 amino acids from the Central region of human PALB2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PALB2

Target: PALB2 (Partner and Localizer of BRCA2 (PALB2))

Alternative Name: PALB2

Background: This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2.Synonyms: FANCN, Partner and localizer of BRCA2

Molecular Weight: 131295 Da

Gene ID: 79728

NCBI Accession: NP_078951

Pathways: DNA Damage Repair