PARP2 antibody (N-Term)

Catalog No. ABIN953996

The Rabbit Polyclonal anti-PARP2 antibody is suitable to detect PARP2 in samples from Human and Mouse. It has been validated for WB and EIA.

Quick Overview for PARP2 antibody (N-Term) (ABIN953996)

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARP2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-PARP2 Antibody

Binding Specificity: AA 9-41, N-Term

Specificity: This antibody recognizes Human and Mouse PARP2 (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 9-41 amino acids from the N-terminal region of human PARP2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PARP2

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Alternative Name: PARP2

Background: PARP2 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.Synonyms: ADPRT2, ADPRTL2, EC=2.4.2.30, NAD(+) ADP-ribosyltransferase 2, PARP 2, PARP-2, Poly [ADP-ribose] polymerase 2, Poly[ADP-ribose] synthetase 2, pADPRT-2

Molecular Weight: 63397 Da

Gene ID: 11546

NCBI Accession: NP_033762

Pathways: DNA Damage Repair