PIGP antibody (N-Term)

Catalog No. ABIN954138

Product Details anti-PIGP Antibody

Target: PIGP (Phosphatidylinositol Glycan Anchor Biosynthesis, Class P (PIGP))

Binding Specificity: AA 1-30, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIGP antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes PIGP at N-term.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 1-30aa) of human PIGP.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PIGP

Target: PIGP (Phosphatidylinositol Glycan Anchor Biosynthesis, Class P (PIGP))

Alternative Name: PIGP (PIGP Products)

Synonyms: DCRC antibody, DCRC-S antibody, DSCR5 antibody, DSRC antibody, dcrc antibody, dsrc antibody, dscr5 antibody, dcrc-s antibody, Dcrc antibody, Dscr5 antibody, PIGP antibody, Pigp antibody, wu:fc66d08 antibody, zgc:73366 antibody, phosphatidylinositol glycan anchor biosynthesis class P antibody, phosphatidylinositol glycan anchor biosynthesis, class P antibody, PIGP antibody, pigp antibody, Pigp antibody

Background: The PIGP gene encodes an enzyme involved in the first step of glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. The encoded protein is a component of the GPI-N-acetylglucosaminyltransferase complex that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). This gene is located in the Down Syndrome critical region on chromosome 21 and is a candidate for the pathogenesis of Down syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.Synonyms: DCRC, DCRC-S, DSCR5, DSCRC, Down syndrome critical region protein 5, Down syndrome critical region protein C, Phosphatidylinositol N-acetylglucosaminyltransferase subunit P

Gene ID: 51227

NCBI Accession: NP_710148

Pathways: Inositol Metabolic Process