PON1 antibody (Middle Region)

Catalog No. ABIN954245

The Rabbit Polyclonal anti-PON1 antibody is suitable to detect PON1 in samples from Human. It has been validated for WB, FACS, IHC (p) and EIA.

Quick Overview for PON1 antibody (Middle Region) (ABIN954245)

Target: PON1 (Paraoxonase 1 (PON1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PON1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-PON1 Antibody

Binding Specificity: AA 121-149, Middle Region

Specificity: This antibody recognizes Human PON1 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 121-149 amino acids from the Central region of human PON1.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PON1

Target: PON1 (Paraoxonase 1 (PON1))

Alternative Name: PON1

Background: The enzyme encoded by this gene is an Arylesterase that mainly hydrolyzes Paroxon to produce p-Nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.Synonyms: A-esterase 1, Aromatic esterase 1, EC=3.1.1.2, EC=3.1.8.1, K-45, PON, PON 1, PON-1, Serum aryldialkylphosphatase 1, Serum paraoxonase/arylesterase 1

Molecular Weight: 39731 Da

Gene ID: 5444

NCBI Accession: NP_000437