RUNX3 antibody (Middle Region)

Catalog No. ABIN954644

The Rabbit Polyclonal anti-RUNX3 antibody is suitable to detect RUNX3 in samples from Human. It has been validated for WB and EIA.

Quick Overview for RUNX3 antibody (Middle Region) (ABIN954644)

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RUNX3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-RUNX3 Antibody

Binding Specificity: AA 167-197, Middle Region

Purification: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 167-197 amino acids from the Central region of Human RUNX3 Genename: RUNX3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for RUNX3

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Alternative Name: RUNX3

Background: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: AML2, Acute myeloid leukemia 2 protein, CBF-alpha-3, CBFA3, Core-binding factor subunit alpha-3, Oncogene AML-2, PEA2-alpha C, PEBP2-alpha C, PEBP2A3, Polyomavirus enhancer-binding protein 2 alpha C subunit, Runt-related transcription factor 3, SL3-3 enhancer factor 1 alpha C subunit, SL3/AKV core-binding factor alpha C subunit

Gene ID: 864

NCBI Accession: NP_001026850