SNX13 antibody (C-Term)

Catalog No. ABIN954885

Product Details anti-SNX13 Antibody

Target: SNX13 (Sorting Nexin 13 (SNX13))

Binding Specificity: AA 779-807, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNX13 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects human SNX13 at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Purified through a protein A column; followed by peptide affinity purification.

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 779-807aa) of human Sorting nexin-13 (SNX13).

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SNX13

Target: SNX13 (Sorting Nexin 13 (SNX13))

Alternative Name: Sorting Nexin-13 (SNX13) (SNX13 Products)

Background: SNX13 gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.Synonyms: KIAA0713, RGS domain- and PHOX domain-containing protein

Gene ID: 23161

NCBI Accession: NP_055947

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling