STAR antibody (Middle Region)

Catalog No. ABIN954970

This Rabbit Polyclonal antibody specifically detects STAR in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for STAR antibody (Middle Region) (ABIN954970)

Target: STAR (Steroidogenic Acute Regulatory Protein (STAR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAR antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-STAR Antibody

Binding Specificity: AA 87-117, Middle Region

Specificity: This antibody recognizes Human STAR (Center).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 87-117 amino acids from the Central region of Human STAR

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for STAR

Target: STAR (Steroidogenic Acute Regulatory Protein (STAR))

Alternative Name: STAR / STARD1

Background: The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13Synonyms: START domain-containing protein 1, Steroidogenic acute regulatory protein mitochondrial

Molecular Weight: 31914 Da

Gene ID: 6770

NCBI Accession: NP_000340

Pathways: Metabolism of Steroid Hormones and Vitamin D, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis