TBX3 antibody (Middle Region)
Quick Overview for TBX3 antibody (Middle Region) (ABIN955111)
Target
See all TBX3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 309-338, Middle Region
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Specificity
- This antibody reacts to TBX3.
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Cross-Reactivity (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity chromatography on Protein A
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Immunogen
- KLH conjugated synthetic peptide between 309-338 amino acids from the Central region of human TBX3
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Isotype
- Ig Fraction
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS, 0.09 % (W/V) sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- TBX3 (T-Box 3 (TBX3))
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Alternative Name
- TBX3
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Background
- This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms, however, the full length nature of one variant has not been determined.Synonyms: T-box protein 3, T-box transcription factor TBX3
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Molecular Weight
- 79389 Da
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Gene ID
- 6926
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NCBI Accession
- NP_005987
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Pathways
- Hormone Transport, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Target
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