Tec Protein Tyrosine Kinase (TEC) (AA 25-55), (N-Term) antibody

Catalog No. ABIN955136

The Rabbit Polyclonal anti-Tec Protein Tyrosine Kinase antibody is suitable to detect Tec Protein Tyrosine Kinase in samples from Human. It has been validated for WB and EIA.

Quick Overview for Tec Protein Tyrosine Kinase (TEC) (AA 25-55), (N-Term) antibody (ABIN955136)

Target: Tec Protein Tyrosine Kinase (TEC)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details

Binding Specificity: AA 25-55, N-Term

Specificity: This antibody detects Human TEC (N-term). Other species not tested.

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 25-55 amino acids from the N-terminal region of human TEC

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details

Target: Tec Protein Tyrosine Kinase (TEC)

Alternative Name: TEC

Background: TEC belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.Synonyms: PSCTK4, Tyrosine-protein kinase Tec

Molecular Weight: 73581 Da

Gene ID: 7006

NCBI Accession: NP_003206

Pathways: Fc-epsilon Receptor Signaling Pathway