TNIP2 antibody (Middle Region)
Quick Overview for TNIP2 antibody (Middle Region) (ABIN955282)
Target
See all TNIP2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 164-194, Middle Region
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Specificity
- This antibody detects TNIP2 (Center).
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Cross-Reactivity (Details)
- Species reactivity (tested):Human
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Purification
- Protein A column followed by peptide affinity purification
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Immunogen
- KLH conjugated synthetic peptide between 164-194 amino acids from the Central region of human TNIP2
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Isotype
- Ig Fraction
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
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- TNIP2 (TNFAIP3 Interacting Protein 2 (TNIP2))
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Alternative Name
- TNIP2
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Background
- TNIP2 binds to the C-terminal zinc finger domain of A20 (TNFAIP3, MIM 191163) and is involved in activation of the ERK (see MAPK3, MIM 601795) MAP kinase pathway in various cell types (Van Huffel et al., 2001 [PubMed 11390377], Papoutsopoulou et al., 2006 [PubMed 16633345]).Synonyms: A20-binding inhibitor of NF-kappa-B activation 2, ABIN-2, ABIN2, FLIP1, Fetal liver LKB1-interacting protein, TNFAIP3-interacting protein 2
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Gene ID
- 79155
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NCBI Accession
- NP_001154999
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Pathways
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin
Target
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