APOA5 antibody

Catalog No. ABIN965569

This Monoclonal antibody specifically detects APOA5 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for APOA5 antibody (ABIN965569)

Target: APOA5 (Apolipoprotein A-V (APOA5))

Reactivity: Human

Host: Please inquire

Clonality: Monoclonal

Conjugate: This APOA5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-APOA5 Antibody

Specificity: Ni-NTA purified recombinant human Apoa5 expressed in E. Coli strain BL21 (DE3).

Purification: Antibodies are purified by protein G affinity chromatography.

Isotype: IgG1

Application Details

Application Notes: Western Blot: Dilution 1: 1,000- 1: 2,000
Suggested ELISA dilution 1: 4,000
ptimized dilution must be determined by end user.

Restrictions: For Research Use only

Handling

Storage: -20 °C

Target Details for APOA5

Target: APOA5 (Apolipoprotein A-V (APOA5))

Alternative Name: APOA5

Background: Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50-70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor- agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Despite these compelling molecular biology data, relatively little is known about ApoA5 protein in human serum. This antibody pair detected recombinant apoa5 protein in sandwich ELISA format and could be potential reagents for the development of clinical diagnostic kits.

Gene ID: 116519

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism