Bcl-2 antibody
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- Target See all Bcl-2 (BCL2) Antibodies
- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
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Reactivity
- Human, Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Bcl-2 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Immunofluorescence (IF)
- Purification
- Ascitic fluid
- Immunogen
- Synthetic peptide corresponding to residues surrounding BCL-2, conjugated to KLH.
- Clone
- 8E12
- Isotype
- IgG1
- Top Product
- Discover our top product BCL2 Primary Antibody
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- Application Notes
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Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - Restrictions
- For Research Use only
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- Format
- Liquid
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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p53, Bcl-2 and AgNOR tissue markers: model approach in predicting prostate cancer characteristics." in: The Journal of international medical research, Vol. 37, Issue 6, pp. 1868-76, (2010) (PubMed).
: "
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p53, Bcl-2 and AgNOR tissue markers: model approach in predicting prostate cancer characteristics." in: The Journal of international medical research, Vol. 37, Issue 6, pp. 1868-76, (2010) (PubMed).
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- Target
- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
- Alternative Name
- BCL-2 (BCL2 Products)
- Background
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This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.
Tissue specificity: Expressed in a variety of tissues.
Synonyms: Bcl-2, BCL2 - Molecular Weight
- 26kDa
- Gene ID
- 596
- Pathways
- MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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