Caspase 1 antibody (N-Term)

Catalog No. ABIN965750

The Rabbit Polyclonal anti-Caspase 1 antibody is suitable to detect Caspase 1 in samples from Fall Armyworm. It has been validated for IHC.

Quick Overview for Caspase 1 antibody (N-Term) (ABIN965750)

Target: Caspase 1 (CASP1)

Reactivity: Fall Armyworm

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Caspase 1 Antibody

Binding Specificity: N-Term

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of fall armyworm (Spodoptera frugiperda) CASP1(Caspase-1 protein)

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for Caspase 1

Target: Caspase 1 (CASP1)

Alternative Name: CASP1

Background: CASP1(Caspase-1) is involved in the activation cascade of caspases responsible for apoptosis execution. The Caspase-1 is inhibited by the baculovirus anti-apoptotic protein p35. It cleaves p35 and nuclear immunophilin FKBP46. Caspase-1 contains a heterodimer of a 19/18 kDa (p19/18) and a 12 kDa (p12) subunit. The two subunits are derived from the precursor sequence by an autocatalytic mechanism. Caspase-1 belongs to the peptidase C14 family.

Pathways: Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome