SLC6A3 antibody (N-Term)

Catalog No. ABIN965973

Cited in 2+ publications. The Rabbit Polyclonal anti-SLC6A3 antibody (ABIN965973) specifically detects SLC6A3 in IHC. The antibody is reactive with Human samples.

Quick Overview for SLC6A3 antibody (N-Term) (ABIN965973)

Target: SLC6A3 (Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC6A3 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-SLC6A3 Antibody

Binding Specificity: N-Term

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human DAT(Sodium-dependent dopamine transporter)

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-SLC6A3 antibody (ABIN965973)

Pristupa, Wilson, Hoffman, Kish, Niznik: "Pharmacological heterogeneity of the cloned and native human dopamine transporter: disassociation of [3H]WIN 35,428 and [3H]GBR 12,935 binding." in: Molecular pharmacology, Vol. 45, Issue 1, pp. 125-35, (1994) (PubMed).

Vandenbergh, Persico, Uhl: "A human dopamine transporter cDNA predicts reduced glycosylation, displays a novel repetitive element and provides racially-dimorphic TaqI RFLPs." in: Brain research. Molecular brain research, Vol. 15, Issue 1-2, pp. 161-6, (1992) (PubMed).

Target Details for SLC6A3

Target: SLC6A3 (Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3))

Alternative Name: DAT

Background: DAT(Sodium-dependent dopamine transporter)is an amine transporter. DAT terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals. This protein is the target of psychomotor stimulants such as amphetamines or cocaine. It belongs to the sodium: neurotransmitter symporter (SNF) family.

Pathways: Dopaminergic Neurogenesis