DUSP6 antibody (N-Term)

Catalog No. ABIN966015

Cited in 2+ publications. The Rabbit Polyclonal anti-DUSP6 antibody (ABIN966015) specifically detects DUSP6 in IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for DUSP6 antibody (N-Term) (ABIN966015)

Target: DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP6 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-DUSP6 Antibody

Binding Specificity: N-Term

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human DUSP6(Dual specificity protein phosphatase 6)

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-DUSP6 antibody (ABIN966015)

Furukawa, Yatsuoka, Youssef, Abe, Yokoyama, Fukushige, Soeda, Hoshi, Hayashi, Sunamura, Kobari, Horii: "Genomic analysis of DUSP6, a dual specificity MAP kinase phosphatase, in pancreatic cancer." in: Cytogenetics and cell genetics, Vol. 82, Issue 3-4, pp. 156-9, (1999) (PubMed).

Groom, Sneddon, Alessi, Dowd, Keyse: "Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase." in: The EMBO journal, Vol. 15, Issue 14, pp. 3621-32, (1996) (PubMed).

Target Details for DUSP6

Target: DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

Alternative Name: DUSP6

Background: DUSP6 (Dual specificity protein phosphatase 6) inactivates MAP kinases. DUSP6 has a specificity for the ERK family and it belongs to the protein-tyrosine phosphatase family and non-receptor class dual specificity subfamily. DUSP6 contains 1 rhodanese domain and 1 tyrosine-protein phosphatase domain.

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades