Estrogen Receptor alpha antibody
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- Target See all Estrogen Receptor alpha (ESR1) Antibodies
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Estrogen Receptor alpha antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human ESR1 expressed in E. Coli.
- Clone
- 6B6
- Isotype
- IgG1
- Top Product
- Discover our top product ESR1 Primary Antibody
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- Application Notes
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Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - Restrictions
- For Research Use only
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- Format
- Liquid
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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Beyond informed consent." in: Medical economics, Vol. 87, Issue 4, pp. 25, 30, 32, (2010) (PubMed).
: "
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Beyond informed consent." in: Medical economics, Vol. 87, Issue 4, pp. 25, 30, 32, (2010) (PubMed).
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- Target
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
- Alternative Name
- ESR1 (ESR1 Products)
- Background
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This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.
Synonyms: ER, ESR, Era, ESRA, NR3A1, DKFZp686N23123, ESR1 - Molecular Weight
- 66kDa
- Gene ID
- 2099
- Pathways
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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