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Estrogen Receptor alpha antibody

ESR1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 6B6 unconjugated
Catalog No. ABIN966095
  • Target See all Estrogen Receptor alpha (ESR1) Antibodies
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
    Reactivity
    • 466
    • 168
    • 161
    • 18
    • 17
    • 10
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Human
    Host
    • 374
    • 99
    • 1
    • 1
    Mouse
    Clonality
    • 357
    • 119
    • 1
    Monoclonal
    Conjugate
    • 215
    • 32
    • 21
    • 19
    • 15
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    This Estrogen Receptor alpha antibody is un-conjugated
    Application
    • 343
    • 158
    • 140
    • 112
    • 94
    • 84
    • 80
    • 54
    • 32
    • 28
    • 23
    • 15
    • 9
    • 7
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human ESR1 expressed in E. Coli.
    Clone
    6B6
    Isotype
    IgG1
    Top Product
    Discover our top product ESR1 Primary Antibody
  • Application Notes
    Western Bloting: 1/500 - 1/2000.
    Immunohistochemistry: 1/200 - 1/1000.
    Immunofluorescence: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Saylor: "Beyond informed consent." in: Medical economics, Vol. 87, Issue 4, pp. 25, 30, 32, (2010) (PubMed).

  • Target
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
    Alternative Name
    ESR1 (ESR1 Products)
    Background
    This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.
    Synonyms: ER, ESR, Era, ESRA, NR3A1, DKFZp686N23123, ESR1
    Molecular Weight
    66kDa
    Gene ID
    2099
    Pathways
    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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