IGF1R antibody

Catalog No. ABIN966345

Cited in 1 publication. The Rabbit Polyclonal anti-IGF1R antibody (ABIN966345) specifically detects IGF1R in IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for IGF1R antibody (ABIN966345)

Target: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGF1R antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-IGF1R Antibody

Specificity: IGF-1R (Ab-1161) antibody detects endogenous levels of total IGF-1R protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human IGF-1R around the phosphorylation site of tyrosine 1161 (D-I-YP-E-T).

Application Details

Application Notes: WB: 1:500~1:1000
IHC: 1:50~1:100.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-IGF1R antibody (ABIN966345)

Hernández-Sánchez, Blakesley, Kalebic, Helman, LeRoith: "The role of the tyrosine kinase domain of the insulin-like growth factor-I receptor in intracellular signaling, cellular proliferation, and tumorigenesis." in: The Journal of biological chemistry, Vol. 270, Issue 49, pp. 29176-81, (1996) (PubMed).

Target Details for IGF1R

Target: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Alternative Name: IGF-1R

Pathways: RTK Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy