Insulin antibody

Catalog No. ABIN966408

This anti-Insulin antibody is a Guinea Pig Polyclonal antibody detecting Insulin in IHC (p), IHC (fp) and IHC (fro). Suitable for Human.

Quick Overview for Insulin antibody (ABIN966408)

Target: Insulin (INS)

Reactivity: Human

Host: Guinea Pig

Clonality: Polyclonal

Conjugate: This Insulin antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Insulin Antibody

Specificity: Insulin is a hormone that is synthesized, stored and secreted by b-cells of islets of Langerhans of the pancreas.

Purification: Concentrated.

Immunogen: Human insulin.

Application Details

Application Notes: IHC: 1:50-200
Staining Procedure: This antibody can be used on formalin-fixed, paraffin-embedded tissue sections. Prolonged fixation in buffered formalin can destroy the epitope. The antibody may be used at a dilution of 1:50 to 1:200 in IHC. This product is also effective on frozen tissue sections. The optimal conditions should be determined by the individual laboratory. Form Supplied: Total immunoglobulin fraction.

Comment:

Cellular Localization: Cytoplasmic.
Recommended Positive Control: Human pancreas

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml.

Buffer: 20 mM tris-borate, 150 mM Sodium Chloride, BMC-6 carrier polysaccharides, carrier protein, pH 7.5

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for Insulin

Target: Insulin (INS)

Alternative Name: Insulin

Molecular Weight: 6 kDa

Pathways: NF-kappaB Signaling, RTK Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation