MAP2K1 antibody (Mitogen-Activated Protein Kinase Kinase 1)

Details for Product anti-MAP2K1 Antibody No. ABIN966564, Supplier: Log in to see
Antigen
  • Mek1
  • CFC3
  • MAPKK1
  • MEK1
  • MKK1
  • PRKMK1
  • MEKK1
  • Prkmk1
  • mek-2
  • si:ch211-242m18.2
  • wu:fj56a12
  • wu:fj61b01
  • zgc:56557
  • ATMEK1
  • F20B18.180
  • F20B18_180
  • MAP kinase/ ERK kinase 1
  • MITOGEN ACTIVATED PROTEIN KINASE KINASE
  • MITOGEN ACTIVATED PROTEIN KINASE KINASE 1
  • NMAPKK
  • MEK
  • mitogen activated protein kinase kinase 1
  • mitogen-activated protein kinase kinase 1
  • mitogen-activated protein kinase kinase 1 L homeolog
  • MAP kinase/ ERK kinase 1
  • Map2k1
  • MAP2K1
  • map2k1.L
  • map2k1
  • MEK1
Alternatives
anti-Human MAP2K1 antibody for Western Blotting
Reactivity
Human, Mouse (Murine), Rat (Rattus)
727
476
422
105
81
44
30
24
21
19
10
8
5
5
4
4
4
1
1
Host
Rabbit
599
128
5
3
2
1
Clonality
Polyclonal
Conjugate
This MAP2K1 antibody is un-conjugated
20
20
19
12
9
9
9
8
6
6
6
6
6
6
6
6
6
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC)
590
288
214
145
133
79
30
25
24
10
10
8
7
6
4
2
1
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human MEK1 around the phosphorylation site of threonine 291 (P-R-TP-P-G).
Specificity MEK1 (Ab-291) antibody detects endogenous levels of total MEK1 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Plasmids, Primers & others Plasmids, Primers & others MAP2K1 products on genomics-online (e.g. as negative or positive controls)
Antigen Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1)
Alternative Name MEK1 (MAP2K1 Antibody Abstract)
Pathways MAPK Signaling, RTK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Burroughs, Oh, Barrett, DiAugustine et al.: "Phosphatidylinositol 3-kinase and mek1/2 are necessary for insulin-like growth factor-I-induced vascular endothelial growth factor synthesis in prostate epithelial cells: a role for hypoxia-inducible ..." in: Molecular cancer research : MCR, Vol. 1, Issue 4, pp. 312-22, 2003 (PubMed).

Schramek, Feifel, Marschitz, Golochtchapova, Gstraunthaler, Montesano: "Loss of active MEK1-ERK1/2 restores epithelial phenotype and morphogenesis in transdifferentiated MDCK cells." in: American journal of physiology. Cell physiology, Vol. 285, Issue 3, pp. C652-61, 2003 (PubMed).

Piatelli, Doughty, Chiles: "Requirement for a hsp90 chaperone-dependent MEK1/2-ERK pathway for B cell antigen receptor-induced cyclin D2 expression in mature B lymphocytes." in: The Journal of biological chemistry, Vol. 277, Issue 14, pp. 12144-50, 2002 (PubMed).

Morgan, Labno, Van Seventer, Denny, Straus, Burkhardt: "Superantigen-induced T cell:B cell conjugation is mediated by LFA-1 and requires signaling through Lck, but not ZAP-70." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 10, pp. 5708-18, 2001 (PubMed).

Did you look for something else?