PPARG antibody

Catalog No. ABIN966887

There are 3+ publications for this product available. The Monoclonal anti-PPARG antibody is suitable to detect PPARG in samples from Human. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for PPARG antibody (ABIN966887)

Target: PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

Reactivity: Human

Host: Please inquire

Clonality: Monoclonal

Conjugate: This PPARG antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-PPARG Antibody

Specificity: Ni-NTA purified truncated recombinant PPARG expressed in E. Coli strain BL21 (DE3)

Purification: Crude ascites.

Isotype: IgG1

Application Details

Application Notes: Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
IHC(F): 1: 500- 1: 2,000
IF : 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: -20 °C

References for anti-PPARG antibody (ABIN966887)

Yang, Ma, Ma, Fogo: "Peroxisome proliferator-activated receptor-gamma agonist is protective in podocyte injury-associated sclerosis." in: Kidney international, Vol. 69, Issue 10, pp. 1756-64, (2006) (PubMed).

Weng, Chen, Pinzone, Ringel, Chen: "Beyond peroxisome proliferator-activated receptor gamma signaling: the multi-facets of the antitumor effect of thiazolidinediones." in: Endocrine-related cancer, Vol. 13, Issue 2, pp. 401-13, (2006) (PubMed).

Ahdjoudj, Kaabeche, Holy, Fromigué, Modrowski, Zérath, Marie: "Transforming growth factor-beta inhibits CCAAT/enhancer-binding protein expression and PPARgamma activity in unloaded bone marrow stromal cells." in: Experimental cell research, Vol. 303, Issue 1, pp. 138-47, (2004) (PubMed).

Target Details for PPARG

Target: PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

Alternative Name: PPARG

Background: PPAR gamma(PPARG), which encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. Three subtypes of PPARs are known: PPAR-alpha, PPARdelta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

Gene ID: 5468

Pathways: MAPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation