CDK5 antibody (Cyclin-Dependent Kinase 5)

Details for Product anti-CDK5 Antibody No. ABIN969041
Target
Reactivity
Human, Monkey, Rat
168
113
108
18
15
15
15
14
13
12
9
9
5
5
3
3
3
3
3
2
1
1
1
Host
Mouse
127
44
Clonality (Clone)
Monoclonal ()
Conjugate
This CDK5 antibody is un-conjugated
12
7
6
5
4
4
4
4
4
2
2
2
2
2
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
129
63
36
29
27
22
21
15
14
7
4
3
3
Options
Immunogen Purified recombinant fragment of human CDK5 expressed in E. Coli.
Clone 4-00E-04
Isotype IgG1
Purification Ascites
Target
Alternative Name CDK5 (CDK5 Antibody Abstract)
Background Function: Probably involved in the control of the cell cycle. Interacts with D1 and D3-type G1 cyclins. Can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. Also interacts with p35 which activates the kinase.
Molecular Weight 35 kDa
Gene ID 1020
HGNC 1020
Pathways Cell Division Cycle, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Images
Image no. 1 for anti-Cyclin-Dependent Kinase 5 (CDK5) antibody (ABIN969041) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Image no. 2 for anti-Cyclin-Dependent Kinase 5 (CDK5) antibody (ABIN969041) Figure 3: Immunofluorescence analysis of GC7901 cells using CDK5 mouse mAb (green) . ...
Image no. 3 for anti-Cyclin-Dependent Kinase 5 (CDK5) antibody (ABIN969041) Figure 4: Immunohistochemical analysis of paraffin-embedded cerebellum tissues (left)...
Image no. 4 for anti-Cyclin-Dependent Kinase 5 (CDK5) antibody (ABIN969041) Figure 2: Flow cytometric analysis of K562 cells using CDK5 mouse mAb (green) and neg...
Image no. 5 for anti-Cyclin-Dependent Kinase 5 (CDK5) antibody (ABIN969041) Figure 5: Western blot analysis using CDK5 mouse mAb against Hela (1), K562 (2), PC-1...
Product cited in: Choi, Lee, Park, Sung, Lee, Shin, Ryu, Kim: "Single-nucleotide polymorphisms in the promoter of the CDK5 gene and lung cancer risk in a Korean population." in: Journal of human genetics, Vol. 54, Issue 5, pp. 298-303, 2009 (PubMed).

Zhang, Herrup: "Cdk5 and the non-catalytic arrest of the neuronal cell cycle." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 22, pp. 3487-90, 2008 (PubMed).