PAI1 antibody
(2 references)Quick Overview for PAI1 antibody (ABIN969566)
Target
See all PAI1 (SERPINE1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- SERPINE1 Antibody
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Purification
- Purified antibody
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Immunogen
- Purified recombinant fragment of human SERPINE1 expressed in E. Coli.
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Isotype
- IgG1
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anti-Plasminogen Activator Inhibitor 1 (SERPINE1) antibody
SERPINE1 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal C6 unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 24-402) antibodySERPINE1 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (Internal Region) antibodyVerified SERPINE1 Reactivity: Human WB, IHC, ELISA Host: Goat Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 86-185) antibodySERPINE1 Reactivity: Human WB, ELISA, IP Host: Mouse Monoclonal 3F2 unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) antibodySERPINE1 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal C4 unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 24-402) antibodySERPINE1 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) antibodySERPINE1 Reactivity: Human, Monkey WB, IHC, FACS, IHC (p) Host: Mouse Monoclonal 6F3 unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 141-389) antibodySERPINE1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 24-398) antibodySERPINE1 Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 1-402) antibodySERPINE1 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
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Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "CXCL12-mediated induction of plasminogen activator inhibitor-1 expression in human CXCR4 positive astroglioma cells." in: Biological & pharmaceutical bulletin, Vol. 32, Issue 4, pp. 573-7, (2009) (PubMed).
: "Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach." in: Clinica chimica acta; international journal of clinical chemistry, Vol. 402, Issue 1-2, pp. 189-92, (2009) (PubMed).
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: "CXCL12-mediated induction of plasminogen activator inhibitor-1 expression in human CXCR4 positive astroglioma cells." in: Biological & pharmaceutical bulletin, Vol. 32, Issue 4, pp. 573-7, (2009) (PubMed).
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- PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
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Alternative Name
- SERPINE1
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Background
- This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 45 kDa
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UniProt
- P05121
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Pathways
- p53 Signaling, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
Target
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