ASIC1 Products
(Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2))
Categories
This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012].
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Featured ASIC1 Categories
ASIC1 Antibodies
High quality antibodies with extensive validation data.
ASIC1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ASIC1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
Validations
- (5)
Cat. No.
ABIN2776229
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (3)
Cat. No.
ABIN653218
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN2613387
Quantity
100 μg
Datasheet
Datasheet
Recommended ASIC1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6212694
Quantity
96 tests
Datasheet
Datasheet
Recommended ASIC1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305626
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305628
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3089318
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ASIC1 products
: "Mambalgin-2 Inhibits Lung Adenocarcinoma Growth and Migration by Selective Interaction With ASIC1/α-ENaC/γ-ENaC Heterotrimer." in: Frontiers in oncology, Vol. 12, pp. 904742, (2022) (PubMed).: "Mambalgin-2 Inhibits Growth, Migration, and Invasion of Metastatic Melanoma Cells by Targeting the Channels Containing an ASIC1a Subunit Whose Up-Regulation Correlates with Poor Survival Prognosis." in: Biomedicines, Vol. 9, Issue 10, (2021) (PubMed).
: "Genetic exploration of the role of acid-sensing ion channels." in: Neuropharmacology, Vol. 94, pp. 99-118, (2015) (PubMed).
: "Knockdown of acid-sensing ion channel 1a (ASIC1a) suppresses disease phenotype in SCA1 mouse model." in: Cerebellum (London, England), Vol. 13, Issue 4, pp. 479-90, (2014) (PubMed).
: "Connective tissue growth factor regulates retinal neovascularization through p53 protein-dependent transactivation of the matrix metalloproteinase (MMP)-2 gene." in: The Journal of biological chemistry, Vol. 287, Issue 48, pp. 40570-85, (2012) (PubMed).
: "Black mamba venom peptides target acid-sensing ion channels to abolish pain." in: Nature, Vol. 490, Issue 7421, pp. 552-5, (2012) (PubMed).
: "Identification of a calcium permeable human acid-sensing ion channel 1 transcript variant." in: The Journal of biological chemistry, Vol. 285, Issue 53, pp. 41852-62, (2010) (PubMed).
Synonyms and alternative names related to ASIC1
acid sensing ion channel subunit 1 (ASIC1), acid sensing ion channel subunit 1 (Asic1), acid sensing ion channel subunit 1 (asic1), acid-sensing (proton-gated) ion channel 1 (Asic1), SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 (SMARCD1), ACCN2, Accn2, AI843610, ASIC, ASIC1, ASIC1a, B530003N02Rik, BNaC2Protein level used designations for ASIC1
- Cation channel, amiloride-sensitive, neuronal, 2
- acid-sensing ion channel 1
- acid-sensing ion channel 1a protein
- amiloride-sensitive cation channel 2, neuronal
- brain sodium channel 2
- BNaC2
- proton gated cation channel ASIC1
- Amiloride-sensitive cation channel 2, neuronal
- acid sensing ion channel
- degenerin 2
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1
- acid-sensing (proton-gated) ion channel 1
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