ASIC3 Products
(Amiloride-Sensitive Cation Channel 3 (ACCN3))
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This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012].
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Featured ASIC3 Categories
ASIC3 Antibodies
High quality antibodies with extensive validation data.
ASIC3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ASIC3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7143004
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN202724
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN5571842
Quantity
100 μL
Datasheet
Datasheet
Recommended ASIC3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121807
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3089253
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3123872
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ASIC3 products
: "Mambalgin-2 Inhibits Growth, Migration, and Invasion of Metastatic Melanoma Cells by Targeting the Channels Containing an ASIC1a Subunit Whose Up-Regulation Correlates with Poor Survival Prognosis." in: Biomedicines, Vol. 9, Issue 10, (2021) (PubMed).: "Naked mole-rat acid-sensing ion channel 3 forms nonfunctional homomers, but functional heteromers." in: The Journal of biological chemistry, Vol. 293, Issue 5, pp. 1756-1766, (2018) (PubMed).
: "ASIC3 fine-tunes bladder sensory signaling." in: American journal of physiology. Renal physiology, Vol. 315, Issue 4, pp. F870-F879, (2018) (PubMed).
: "Two mechanisms involved in trigeminal CGRP release: implications for migraine treatment." in: Headache, Vol. 53, Issue 1, pp. 67-80, (2013) (PubMed).
Synonyms and alternative names related to ASIC3
amiloride-sensitive cation channel 3 (ACCN3), acid sensing ion channel subunit 3 (ASIC3), acid sensing ion channel subunit 3 (Asic3), acid-sensing (proton-gated) ion channel 3 (Asic3), ACCN3, Accn3, AW742291, DRASIC, SLNAC1, TNaC1, TNAC1Protein level used designations for ASIC3
- amiloride-sensitive cation channel 3
- amiloride-sensitive cation channel 3-like
- DRASIC
- acid sensing ion channel 3
- acid-sensing ion channel 3
- dorsal root ASIC
- proton gated cation channel DRASIC
- amiloride-sensitive cation channel 3, testis
- modulatory subunit of ASIC2a
- neuronal amiloride-sensitive cation channel 3
- proton-gated cation channel subunit
- testis sodium channel 1
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