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B3GALNT1 Products

(beta-1,3-N-Acetylgalactosaminyltransferase 1 (B3GALNT1))

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This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). The encoded protein of this gene does not use N-acetylglucosamine as an acceptor sugar at all. Multiple transcript variants that are alternatively spliced in the 5' UTR have been described\; they all encode the same protein. [provided by RefSeq, Jul 2008].

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Featured B3GALNT1 Categories

B3GALNT1 Antibodies

High quality antibodies with extensive validation data.

B3GALNT1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended B3GALNT1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (3)
  • (1)
Cat. No. ABIN6746248
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF
Validations
  • (1)
Cat. No. ABIN7263771
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application WB
Validations
  • (1)
Cat. No. ABIN6742021
Quantity 100 μL
Datasheet Datasheet

Recommended B3GALNT1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6235833
Quantity 96 tests
Datasheet Datasheet

Recommended B3GALNT1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1346267
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3089693
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3127646
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our B3GALNT1 products

Zumbrun, Hanson, Sinclair, Freedy, Melton-Celsa, Rodriguez-Canales, Hanson, OBrien: "Human intestinal tissue and cultured colonic cells contain globotriaosylceramide synthase mRNA and the alternate Shiga toxin receptor globotetraosylceramide." in: Infection and immunity, Vol. 78, Issue 11, pp. 4488-99, (2010) (PubMed).

Jayaraman, Murthy, Zhu, Curran, Xanthoudakis, Prives: "Identification of redox/repair protein Ref-1 as a potent activator of p53." in: Genes & development, Vol. 11, Issue 5, pp. 558-70, (1997) (PubMed).

Xanthoudakis, Miao, Curran: "The redox and DNA-repair activities of Ref-1 are encoded by nonoverlapping domains." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 1, pp. 23-7, (1994) (PubMed).

Xanthoudakis, Miao, Wang, Pan, Curran: "Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme." in: The EMBO journal, Vol. 11, Issue 9, pp. 3323-35, (1992) (PubMed).

Synonyms and alternative names related to B3GALNT1

beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) (B3GALNT1), beta-1,3-N-acetylgalactosaminyltransferase 1 (B3GALNT1), beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) (B3galnt1), UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1 (B3galnt1), B3GALT3, B3galt3, b3GT3, beta3Gal-T3, galT3, Gb4Cer, GLCT3, GLOB, P, P1

Protein level used designations for B3GALNT1

  • UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase 3
  • UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 3
  • UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1 (Globoside blood group)
  • UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase 1
  • UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1
  • UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1
  • UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase
  • b3Gal-T3
  • beta-1,3-GalNAc-T1
  • beta-1,3-GalTase 3
  • beta-1,3-galactosyltransferase 3
  • beta-3-GalNAc-T1
  • beta-3-Gx-T3
  • beta3Gal-T3
  • beta3GalT3
  • galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase
  • globoside synthase
  • Brainiac 1
  • Globoside blood group
  • Mbrn 1
  • UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase III
  • P antigen synthase
  • P blood group globoside
  • UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 3 (Globoside blood group)
  • UDP-GalNAc:betaGlcNAc beta-1,3-galactosaminyltransferase, polypeptide 1 (Globoside blood group)
  • brainiac1
  • globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase
  • UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 3
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