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CACNA1D Products

(Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D))
Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012].

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Featured CACNA1D Categories

CACNA1D Antibodies

High quality antibodies with extensive validation data.

CACNA1D ELISA Kits

Reliable ELISA kits for a wide range of species.

CACNA1D Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CACNA1D Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Application IHC, WB, IP, IF, ICC, AA
Validations
  • (5)
Cat. No. ABIN361760
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application IHC, WB, IP, IF, ICC, AA
Validations
  • (3)
Cat. No. ABIN2484068
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application IHC, WB, IP, IF, ICC, AA
Validations
  • (3)
Cat. No. ABIN2484067
Quantity 100 μg
Datasheet Datasheet

Recommended CACNA1D ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954270
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954271
Quantity 96 tests
Datasheet Datasheet

Recommended CACNA1D Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3090327
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3090326
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3127830
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CACNA1D products

Guo, Cui, Jiang, Zhang, Jiang: "Proteomics of acute heart failure in a rat post-myocardial infarction model." in: Molecular medicine reports, Vol. 16, Issue 2, pp. 1946-1956, (2018) (PubMed).

Lobeck, Donnelly, Dupree, Mahe, McNeal, Mohanty, Tiao: "Rhesus rotavirus VP6 regulates ERK-dependent calcium influx in cholangiocytes." in: Virology, Vol. 499, pp. 185-195, (2016) (PubMed).

Lu, Sirish, Zhang, Woltz, Li, Timofeyev, Knowlton, Zhang, Yamoah, Chiamvimonvat: "Regulation of gene transcription by voltage-gated L-type calcium channel, Cav1.3." in: The Journal of biological chemistry, Vol. 290, Issue 8, pp. 4663-76, (2015) (PubMed).

Perissinotti, Ethington, Almazan, Martínez-Hernández, Kalil, Koob, Piedras-Rentería: "Calcium current homeostasis and synaptic deficits in hippocampal neurons from Kelch-like 1 knockout mice." in: Frontiers in cellular neuroscience, Vol. 8, pp. 444, (2015) (PubMed).

Núñez-Santana, Oh, Antion, Lee, Hell, Disterhoft: "Surface L-type Ca2+ channel expression levels are increased in aged hippocampus." in: Aging cell, Vol. 13, Issue 1, pp. 111-20, (2014) (PubMed).

Perissinotti, Ethington, Cribbs, Koob, Martin, Piedras-Rentería: "Down-regulation of endogenous KLHL1 decreases voltage-gated calcium current density." in: Cell calcium, Vol. 55, Issue 5, pp. 269-80, (2014) (PubMed).

Liedtke, Yeo, Zhang, Wang, Gignac, Miller, Berglund, Liu: "Highly conductive carbon nanotube matrix accelerates developmental chloride extrusion in central nervous system neurons by increased expression of chloride transporter KCC2." in: Small (Weinheim an der Bergstrasse, Germany), Vol. 9, Issue 7, pp. 1066-75, (2013) (PubMed).

Bissig, Goebel, Berkowitz: "Diminished vision in healthy aging is associated with increased retinal L-type voltage gated calcium channel ion influx." in: PLoS ONE, Vol. 8, Issue 2, pp. e56340, (2013) (PubMed).

Dryanovski, Guzman, Xie, Galteri, Volpicelli-Daley, Lee, Miller, Schumacker, Surmeier: "Calcium entry and ?-synuclein inclusions elevate dendritic mitochondrial oxidant stress in dopaminergic neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 24, pp. 10154-64, (2013) (PubMed).

Hurley, Brandon, Gentleman, Dexter: "Parkinson's disease is associated with altered expression of CaV1 channels and calcium-binding proteins." in: Brain : a journal of neurology, Vol. 136, Issue Pt 7, pp. 2077-97, (2013) (PubMed).

Synonyms and alternative names related to CACNA1D

calcium channel, voltage-dependent, L type, alpha 1D subunit, a (cacna1da), calcium voltage-gated channel subunit alpha1 D (CACNA1D), calcium channel, voltage-dependent, L type, alpha 1D subunit (cacna1d), calcium channel, voltage-dependent, L type, alpha 1D subunit L homeolog (cacna1d.L), calcium voltage-gated channel subunit alpha1 D (Cacna1d), calcium channel, voltage-dependent, L type, alpha 1D subunit (Cacna1d), 8430418G19Rik, C79217, ca(v)1.3, CACH3, CACN4, cacna1d, CACNL1A2, Cacnl1a2, cav1.3, Cav1.3, cav1.3a, Cchl1a, CCHL1A2, Cchl1a2, D-LTCC, isl, SANDD, si:dz136d19.3, si:dz223c6.1

Protein level used designations for CACNA1D

  • L-type calcium channel pore subunit isoform 1.3a
  • gem
  • gemini
  • voltage-dependent L-type calcium channel subunit alpha-1D
  • voltage-gated calcium channel alpha 1D subunit
  • calcium channel, voltage-dependent, L type, alpha 1D subunit
  • voltage-gated calcium channel subunit Cav1.3
  • calcium channel voltage-dependent L type Cav1.3, alpha 1d subunit
  • voltage-dependent L-type calcium channel subunit alpha-1D-like
  • calcium channel, L type, alpha-1 polypeptide
  • calcium channel, neuroendocrine/brain-type, alpha 1 subunit
  • voltage-gated calcium channel alpha 1 subunit
  • voltage-gated calcium channel alpha subunit Cav1.3
  • CaV1.3alpha1
  • RBD
  • brain class D
  • calcium channel alpha-1 subunit
  • voltage-dependent calcium channel subunit alpha1D
  • voltage-gated calcium channel pore forming subunit CaV1.3alpha1 IVS3-IVS4 extracellular linker
  • voltage-gated calcium channel subunit alpha Cav1.3
  • Cav1.3alpha1
  • alpha 1 E
  • CHCACHA1D
  • L-type voltage-gated calcium channel alpha1D subunit ChCaChA1D
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