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CDH15 Products

(M-Cadherin (CDH15))

Categories

This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation. [provided by RefSeq, Jul 2008].

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Featured CDH15 Categories

CDH15 Antibodies

High quality antibodies with extensive validation data.

CDH15 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CDH15 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, ICC, IF, WB
Validations
  • (3)
Cat. No. ABIN6257758
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, WB
Validations
  • (2)
Cat. No. ABIN7146213
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (2)
Cat. No. ABIN719831
Quantity 100 μL
Datasheet Datasheet

Recommended CDH15 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4883712
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6385249
Quantity 96 tests
Datasheet Datasheet

Recommended CDH15 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7321152
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3133760
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3133762
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CDH15 products

Nagata, Kiyono, Okamura, Goto, Matsuo, Ikemoto-Uezumi, Hashimoto: "Interleukin-1beta (IL-1β)-induced Notch ligand Jagged1 suppresses mitogenic action of IL-1β on human dystrophic myogenic cells." in: PLoS ONE, Vol. 12, Issue 12, pp. e0188821, (2017) (PubMed).

Chimen, McGettrick, Apta, Kuravi, Yates, Kennedy, Odedra, Alassiri, Harrison, Martin, Barone, Nayar, Hitchcock, Cunningham, Raza, Filer, Copland, Dick, Robinson, Kalia, Walker, Buckley, Nash et al.: "Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease. ..." in: Nature medicine, Vol. 21, Issue 5, pp. 467-75, (2015) (PubMed).

Kang, Feinleib, Knox, Ketteringham, Krauss: "Promyogenic members of the Ig and cadherin families associate to positively regulate differentiation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 7, pp. 3989-94, (2003) (PubMed).

Hollnagel, Grund, Franke, Arnold: "The cell adhesion molecule M-cadherin is not essential for muscle development and regeneration." in: Molecular and cellular biology, Vol. 22, Issue 13, pp. 4760-70, (2002) (PubMed).

Meigs, Fields, McKee, Casey: "Interaction of Galpha 12 and Galpha 13 with the cytoplasmic domain of cadherin provides a mechanism for beta -catenin release." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 2, pp. 519-24, (2001) (PubMed).

Kaufmann, Kirsch, Irintchev, Wernig, Starzinski-Powitz: "The M-cadherin catenin complex interacts with microtubules in skeletal muscle cells: implications for the fusion of myoblasts." in: Journal of cell science, Vol. 112 ( Pt 1), pp. 55-68, (1999) (PubMed).

Shimoyama, Shibata, Kitajima, Hirohashi: "Molecular cloning and characterization of a novel human classic cadherin homologous with mouse muscle cadherin." in: The Journal of biological chemistry, Vol. 273, Issue 16, pp. 10011-8, (1998) (PubMed).

Kuch, Winnekendonk, Butz, Unvericht, Kemler, Starzinski-Powitz: "M-cadherin-mediated cell adhesion and complex formation with the catenins in myogenic mouse cells." in: Experimental cell research, Vol. 232, Issue 2, pp. 331-8, (1997) (PubMed).

Donalies, Cramer, Ringwald, Starzinski-Powitz: "Expression of M-cadherin, a member of the cadherin multigene family, correlates with differentiation of skeletal muscle cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 18, pp. 8024-8, (1991) (PubMed).

Synonyms and alternative names related to CDH15

cadherin 15 (Cdh15), cadherin 15 (CDH15), AI323380, CDH3, Cdh14, CDH14, CDHM, Mcad, MCAD, MRD3

Protein level used designations for CDH15

  • M cadherin
  • M-cadherin
  • cadherin-14
  • cadherin-15
  • muscle cadherin
  • cadherin-3
  • muscle-cadherin
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