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|Antigen||AT Rich Interactive Domain 3A (BRIGHT-Like) (ARID3A) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This ARID3A antibody is conjugated to Alexa Fluor 647 Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
|Supplier||Log in to see|
Product Details anti-ARID3A AntibodyTarget Details ARID3A Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human DRIL1/ARID3A|
Target Details ARID3AProduct Details anti-ARID3A Antibody Application Details Handling Images back to top
|Alternative Name||Dril1/Arid3a (ARID3A Antibody Abstract)|
ARID3A, also known as DRIL1 in humans and Bright (for B cell regulator of IgH transcription) in mice, are the mammalian homologs of the Drosophila Dri (dead ringer) protein. ARID3A is developmentally regulated and is expressed in a restricted set of cells, including differentiating cells of the gut and salivary glands. ARID3A represents a member of a unique family of transcriptional activators that shares sequence similarity to proteins of SWI/SNF complexes, it contains an A/T-rich DNA-binding (ARID) domain and a distinct domain involved in tetramerization. The gene encoding ARID3A is linked to a marker of Peutz-Jeghers syndrome, which is an autosomal-dominant disorder characterized by melanocytic macules of the lips, multiple gastrointestinal hamartomatous polyps and an increased risk for various neoplasms, including gastrointestinal cancer. E2FBP1 (E2F-1 binding protein 1) is identical to ARID3A in the carboxy terminal region. E2FBP1 appears to lack DNA binding and transactivation domains, and it functions to regulate the transcription of proteins involved in cell proliferation by binding to the transcription factor E2F-1.
Synonyms: ARI3A_HUMAN, ARID domain-containing protein 3A, ARID3A, AT rich interactive domain-containing protein 3A, AT-rich interactive domain-containing protein 3A, B cell regulator of IgH transcription, B-cell regulator of IgH transcription, Bright, dead ringer like 1, Dead ringer-like protein 1, DRIL1, DRIL3, E2F binding protein 1, E2F-binding protein 1, E2FBP1.
Application DetailsProduct Details anti-ARID3A Antibody Target Details ARID3A Handling Images back to top
|Application Notes||IF(IHC-P) 1:50-200|
|Restrictions||For Research Use only|
HandlingProduct Details anti-ARID3A Antibody Target Details ARID3A Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at 4°C|
|Expiry Date||12 months|