COMP Proteins
(Cartilage Oligomeric Matrix Protein (COMP))
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2008].
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18 results
COMP
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
COMP
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
COMP
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
COMP
Origin: Rat
Host: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
COMP
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
COMP
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
COMP
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
COMP
Origin: Rat
Host: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
COMP
Origin: Rat
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
COMP
Origin: Human
Host: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Active
COMP
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
Inactive
COMP
Origin: Human
Host: HEK-293 Cells
Recombinant
> 85% by SDS - PAGE
SDS
COMP
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, ELISA, IP
1 image
COMP
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Latest Publications for our COMP Proteins
: "ADAMTS7 degrades Comp to fuel BMP2-dependent osteogenic differentiation and ameliorate oncogenic potential in osteosarcomas." in: FEBS open bio, Vol. 10, Issue 9, pp. 1856-1867, (2020) (PubMed).: "Characterization of a pseudoachondroplasia-associated mutation (His587-->Arg) in the C-terminal, collagen-binding domain of cartilage oligomeric matrix protein (COMP)." in: The Biochemical journal, Vol. 377, Issue Pt 2, pp. 479-87, (2004) (PubMed).
Aliases for COMP Proteins
cartilage oligomeric matrix protein (COMP) Proteinscartilage oligomeric matrix protein (sce3551) Proteins
cartilage oligomeric matrix protein (CJA_1292) Proteins
cartilage oligomeric matrix protein (Comp) Proteins
COMP Proteins
EDM1 Proteins
EPD1 Proteins
MED Proteins
PSACH Proteins
THBS5 Proteins
TSP5 Proteins
Did you look for something else?
- COMMD9 Proteins
- COMMD7 Proteins
- COMMD6 Proteins
- COMMD5 Proteins
- COMMD4 Proteins
- COMMD3 Proteins
- COMMD2 Proteins
- COMMD1 Proteins
- COLQ Proteins
- Colony Stimulating Factor 3 (Granulocyte) Proteins
- Colony Stimulating Factor 1 (Macrophage) Proteins
- Collagen, Type XXVI, alpha 1 Proteins
- Collagen Type I Proteins
- Collagen IV Proteins
- COLEC12 Proteins
- COLEC11 Proteins
- COLEC10 Proteins
- Cold Inducible RNA Binding Protein Proteins
- COL9A3 Proteins
- COL9A1 Proteins
- Complement C2 Proteins
- Complement C4 Proteins
- Complement Factor B Proteins
- Complement Factor H Proteins
- Complement Factor I Proteins
- Complexin 1 Proteins
- Complexin 4 Proteins
- COMTD1 Proteins
- Cone-Rod Homeobox Proteins
- Connexin 31 Proteins
- Connexin 43/GJA1 Proteins
- Contactin 1 Proteins
- Contactin 4 Proteins
- Contactin 5 Proteins
- Contactin 6 Proteins
- COPA Proteins
- COPB1 Proteins
- COPB2 Proteins
- COPE Proteins
- COPG Proteins
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