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COMP Proteins

(Cartilage Oligomeric Matrix Protein (COMP))
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2008].

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20 results

COMP Protein (C-Term)
COMP Origin: Rat Recombinant > 95 % (SDS-PAGE)
Pubmed 1 reference
Catalog No. ABIN1047991
-15% Promotion 2026
$718.89
$845.75
save $126.86 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 5 to 6 Business Days
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COMP Protein (AA 22-240) (GST-His-Tag)
COMP Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505321
-15% Promotion 2026
$195.43
$229.92
save $34.49 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 14 Business Days
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COMP Protein (His tag)
COMP Origin: Human Host: HEK-293 Cells Recombinant > 90 % by SDS-PAGE.
Catalog No. ABIN7534407
-15% Promotion 2026
$233.75
$275.00
save $41.25 (-15 %)
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Will be delivered in 1 Business Day
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COMP Protein (AA 544-757) (His-IF2DI Tag)
COMP Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Catalog No. ABIN7663008
-15% Promotion 2026
$615.93
$724.62
save $108.69 (-15 %)
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 15 to 19 Business Days
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COMP Protein (AA 123-240) (His tag)
COMP Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % SDS, WB, Imm, PC
Catalog No. ABIN7393391
-15% Promotion 2026
$613.49
$721.75
save $108.26 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
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COMP Protein (AA 35-423) (His tag)
COMP Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC
Catalog No. ABIN7421479
-15% Promotion 2026
$627.11
$737.78
save $110.67 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
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COMP Protein (AA 317-455) (His tag)
COMP Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Catalog No. ABIN7402586
-15% Promotion 2026
$635.62
$747.79
save $112.17 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
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COMP Protein (AA 40-180) (His tag)
COMP Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Catalog No. ABIN7402583
-15% Promotion 2026
$635.62
$747.79
save $112.17 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
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COMP Protein (AA 554-753) (His tag)
COMP Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Catalog No. ABIN7393394
-15% Promotion 2026
$635.62
$747.79
save $112.17 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
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COMP Protein (AA 235-423) (His tag)
COMP Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Catalog No. ABIN7403273
-15% Promotion 2026
$670.53
$788.86
save $118.33 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
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COMP Protein (AA 35-179) (His tag)
COMP Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 97 % SDS, WB, Imm, PC
Catalog No. ABIN7393397
-15% Promotion 2026
$670.53
$788.86
save $118.33 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
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COMP Protein (His tag)
COMP Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Catalog No. ABIN7317991
-15% Promotion 2026
$883.32
$1,039.20
save $155.88 (-15 %)
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
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COMP Protein (AA 21-757) (His tag)
COMP Origin: Human Host: HEK-293 Cells Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN7677624
-15% Promotion 2026
$755.85
$889.23
save $133.38 (-15 %)
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
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COMP Protein (GST tag,His tag)
COMP Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % Inactive
Catalog No. ABIN7668308
-15% Promotion 2026
$1,813.56
$2,133.60
save $320.04 (-15 %)
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
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COMP Protein
COMP Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Catalog No. ABIN3008640
$811.46
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 10 to 18 Business Days
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COMP Protein (Myc-DYKDDDDK Tag)
COMP Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2712452
$956.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
Will be delivered in 11 Business Days
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Details
 
COMP Protein
COMP Origin: Human Host: HEK-293 Cells Recombinant
Catalog No. ABIN1061972
$332.36
Plus shipping costs $50.00
10 μg (More quantities available)
Shipping to: United States
Will be delivered in 6 Business Days
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Details
 
COMP Protein (AA 123-240) (His tag)
COMP Origin: Human Host: Bacteria Recombinant
Catalog No. ABIN7815721
$520.52
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg
Shipping to: United States
Delivery in 7 to 8 Business Days
Details
Details
 
COMP Protein (AA 577-755) (His tag)
COMP Origin: Mouse Host: Bacteria Recombinant
Catalog No. ABIN7819922
$520.52
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg
Shipping to: United States
Delivery in 7 to 8 Business Days
Details
Details
 
COMP Protein (AA 20-755) (His tag)
COMP Origin: Rat Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN7583901
$2,211.00
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 60 to 71 Business Days
Details
Details
 
  • Type Protein
    • Protein
  • Application
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Immunogen (Imm)
    • Positive Control (PC)
    • ELISA
    • Antibody Production (AbP)
    • Immunoprecipitation (IP)
    • Standard (STD)
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Images available
  • Carrier free only
  • Host
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Bacteria
    • Yeast
  • Binding Specificity
    • AA 123-240
    • AA 20-755
    • AA 21-757
    • AA 22-240
    • AA 235-423
    • AA 317-455
    • AA 35-179
    • AA 35-423
    • AA 40-180
    • AA 544-757
    • AA 554-753
    • AA 577-755
    • C-Term
  • Conjugate
    • His tag
    • Un-conjugated
    • GST tag,His tag
    • GST-His-Tag
    • His-IF2DI Tag
    • Myc-DYKDDDDK Tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biological Activity
    • Biologically Active
    • Biologically Inactive
  • Supplier
    • antibodies-online
    • ProteoGenix
    • Abbexa
    • CUSABIO
    • ITSI-Biosciences
    • OriGene

Latest Publications for our COMP Proteins

Wang, Chen, Xiang, Wu, Tang, Ma, Zhang: "ADAMTS7 degrades Comp to fuel BMP2-dependent osteogenic differentiation and ameliorate oncogenic potential in osteosarcomas." in: FEBS open bio, Vol. 10, Issue 9, pp. 1856-1867, (2020) (PubMed).

Spitznagel, Nitsche, Paulsson, Maurer, Zaucke: "Characterization of a pseudoachondroplasia-associated mutation (His587-->Arg) in the C-terminal, collagen-binding domain of cartilage oligomeric matrix protein (COMP)." in: The Biochemical journal, Vol. 377, Issue Pt 2, pp. 479-87, (2004) (PubMed).

Aliases for COMP Proteins

cartilage oligomeric matrix protein (COMP) Proteins
cartilage oligomeric matrix protein (sce3551) Proteins
cartilage oligomeric matrix protein (CJA_1292) Proteins
cartilage oligomeric matrix protein (Comp) Proteins
COMP Proteins
EDM1 Proteins
EPD1 Proteins
MED Proteins
PSACH Proteins
THBS5 Proteins
TSP5 Proteins

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