COX IV Products
(Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))
Categories
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. [provided by RefSeq, Jul 2008].
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Featured COX IV Categories
COX IV Antibodies
High quality antibodies with extensive validation data.
COX IV ELISA Kits
Reliable ELISA kits for a wide range of species.
COX IV Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended COX IV Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ICC, IP
Validations
- (6)
Cat. No.
ABIN7441013
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC, IP
Validations
- (8)
Cat. No.
ABIN2855069
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB, IHC
Validations
- (3)
- (6)
Cat. No.
ABIN2775574
Quantity
100 μL
Datasheet
Datasheet
Recommended COX IV ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966216
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966217
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955218
Quantity
96 tests
Datasheet
Datasheet
Recommended COX IV Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122572
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350115
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350117
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our COX IV products
: "Alpinetin inhibits breast cancer growth by ROS/NF-κB/HIF-1α axis." in: Journal of cellular and molecular medicine, Vol. 24, Issue 15, pp. 8430-8440, (2021) (PubMed).: "A rapid juvenile murine model of nonalcoholic steatohepatitis (NASH): Chronic intermittent hypoxia exacerbates Western diet-induced NASH." in: Life sciences, Vol. 276, pp. 119403, (2021) (PubMed).
: "Fundc1 is necessary for proper body axis formation during embryogenesis in zebrafish." in: Scientific reports, Vol. 9, Issue 1, pp. 18910, (2020) (PubMed).
: "Lower mitochondrial DNA content but not increased mutagenesis associates with decreased base excision repair activity in brains of AD subjects." in: Neurobiology of aging, Vol. 73, pp. 161-170, (2019) (PubMed).
: "Shear stress and oxygen availability drive differential changes in opossum kidney proximal tubule cell metabolism and endocytosis." in: Traffic (Copenhagen, Denmark), Vol. 20, Issue 6, pp. 448-459, (2019) (PubMed).
: "Fine particulate matter induces mitochondrial dysfunction and oxidative stress in human SH-SY5Y cells." in: Chemosphere, Vol. 218, pp. 577-588, (2019) (PubMed).
: "High Tidal Volume Induces Mitochondria Damage and Releases Mitochondrial DNA to Aggravate the Ventilator-Induced Lung Injury." in: Frontiers in immunology, Vol. 9, pp. 1477, (2018) (PubMed).
: "ZIC1 acts a tumor suppressor in breast cancer by targeting survivin." in: International journal of oncology, Vol. 53, Issue 3, pp. 937-948, (2018) (PubMed).
: "Succinate-induced neuronal mitochondrial fission and hexokinase II malfunction in ischemic stroke: Therapeutical effects of kaempferol." in: Biochimica et biophysica acta, Vol. 1863, Issue 9, pp. 2307-2318, (2017) (PubMed).
: "The Ca2+/CaMKK2 axis mediates the telbivudine induced upregulation of creatine kinase: Implications for mechanism of antiviral nucleoside analogs' side effect." in: Biochemical pharmacology, Vol. 146, pp. 224-232, (2017) (PubMed).
Synonyms and alternative names related to COX IV
cytochrome c oxidase subunit 4I1 (COX4I1), cytochrome c oxidase subunit IV isoform 1 (cox4i1), cytochrome c oxidase subunit 4 isoform 1, mitochondrial (LOC412396), cytochrome c oxidase subunit IV isoform 1 (Cox4I1), cytochrome c oxidase subunit IV isoform 1 (COX4I1), cytochrome c oxidase polypeptide IV (LOC780848), cytochrome c oxidase polypeptide IV (BMEII0322), cytochrome c oxidase polypeptide IV (RSal33209_1582), cytochrome c oxidase subunit IV (SJAG_00976), cytochrome c oxidase polypeptide IV (HMPREF0733_11926), cytochrome c oxidase subunit 4I1 (Cox4i1), cytochrome c oxidase subunit 4i1 (Cox4i1), cytochrome c oxidase subunit IV isoform 1 S homeolog (cox4i1.S), Cytochrome c oxidase subunit 4-like (COX4L), AL024441, BcDNA:AT07685, CG10396, COX4, Cox4, cox4, COX4-1, Cox4a, cox4i1, COXIV, coxiv, COX IV, CX41, CX42, Dmel\CG10396, GB20012, IV, mg:bb02d03, zgc:110058Protein level used designations for COX IV
- COX IV-1
- cytochrome c oxidase polypeptide IV
- cytochrome c oxidase subunit 4 isoform 1, mitochondrial
- Cox4-1
- OXPHOS complex IV subunit IV
- cytochrome c oxidase, subunit IVa
- cytochrome c oxidase, subunit 4a
- cytochrome c oxidase, subunit IV
- cytochrome c oxydase subunit 4
- cytochrome c oxidase subunit IV
- cytochrome c oxidase IV subunit
- cytochrome c oxidase subunit IV isoform 1 S homeolog
- CG10396 gene product from transcript CG10396-RB
- CG10396-PA
- CG10396-PB
- COX4L-PA
- COX4L-PB
- cytochrome c oxidase subunit 4-like
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