anti-Human Complement Factor H antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Complement Factor H Antibody (supplied by: Log in to see )

Antigen
Complement Factor H (CFH) Antibodies
  • AHUS1
  • AMBP1
  • ARMD4
  • ARMS1
  • CFHL3
  • FH
  • FHL1
  • HF
  • HF1
  • HF2
  • HUS
  • Mud-1
  • NOM
  • Sas-1
  • Sas1
  • Fh
  • CFH
  • im:7147412
  • si:ch211-207o17.2
  • fH
  • armd4
  • arms1
  • cfh
  • cfhl3
  • fhl1
  • hf1
  • hf2
  • hus
  • complement factor H
  • complement component factor h
  • complement factor H-related protein 5
  • complement factor H L homeolog
  • CFH
  • Cfh
  • cfh
  • LOC100399888
  • LOC100733902
  • cfh.L
Epitope
AA 751-780, Middle Region
24
17
16
15
10
10
4
3
3
2
2
2
2
2
2
1
1
1
1
1
Reactivity
Human
273
37
37
4
4
3
3
2
2
Host
Rabbit
137
112
32
20
2
1
Clonality
Polyclonal
Conjugate
This Complement Factor H antibody is un-conjugated
25
17
8
5
5
5
5
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
220
165
82
42
41
26
26
24
15
11
11
10
9
5
4
2
1
1
1
1
1
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Catalog No. ABIN951646
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
10.885783 ABIN337307 ELISA IHC IHC (p) WB Goat AA 577-588 Log in to see Polyclonal 0
10.885783 ABIN443487 IHC (p) IHC WB Rabbit IgG Center Log in to see Polyclonal 0
10.885783 ABIN462334 ELISA IHC IHC (p) IP WB Mouse IgG1 Log in to see OX-24 0
10.885783 ABIN364283 ELISA FACS IHC IHC (p) IP WB Mouse IgG1 Log in to see OX-24 0
10.885783 ABIN4299968 ELISA FACS IHC (p) IP WB Mouse IgG1 Log in to see OX-24 0
10.885783 ABIN4299971 ELISA IHC (p) IP Mouse IgG2b kappa Log in to see 63G5 0
10.885783 ABIN4299972 IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN654896 IF IHC (p) WB Rabbit Ig Fraction AA 751-780, Center Log in to see Polyclonal 2
1 ABIN492503 EIA FACS IHC (p) IP WB Mouse IgG1 Log in to see OX-24 0
1 ABIN2854706 IHC (p) WB Rabbit IgG Internal Region Log in to see Polyclonal 0
1 ABIN1101458 ELISA IHC IHC (p) Goat IgG Log in to see Polyclonal 0
1 ABIN957771 ELISA IHC IHC (p) IP Mouse IgG2b, kappa Log in to see 63G5 0
1 ABIN372860 EIA IHC (p) WB Goat IgG Internal Region Log in to see Polyclonal 0
1 ABIN1858384 ICC IHC (fro) IHC (p) ELISA WB Mouse IgG AA 860-1231 Log in to see 0
1 ABIN492561 EIA IHC (p) IP WB Mouse IgG1 Log in to see OX-24 0
1 ABIN733847 IHC (p) WB HRP Rabbit IgG AA 1160-1210 Log in to see Polyclonal 0
1 ABIN1723178 FACS IHC (p) IP ELISA WB Mouse IgG1 Log in to see OX-24 0
1 ABIN1734235 IHC (p) ELISA Goat IgG Log in to see Polyclonal 0
1 ABIN1734233 IHC (p) ELISA WB Goat Internal Region Log in to see Polyclonal 0
1 ABIN1832834 IHC IHC (p) WB Rabbit IgG AA 527-618 Log in to see Polyclonal 0

General

Antigen Complement Factor H (CFH) Antibodies
Epitope AA 751-780, Middle Region
(24), (17), (16), (15), (10), (10), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human
(273), (37), (37), (4), (4), (3), (3), (2), (2)
Host Rabbit
(137), (112), (32), (20), (2), (1)
Clonality
Polyclonal
Conjugate This Complement Factor H antibody is un-conjugated
(25), (17), (8), (5), (5), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(220), (165), (82), (42), (41), (26), (26), (24), (15), (11), (11), (10), (9), (5), (4), (2), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-Complement Factor H Antibody

Target Details Complement Factor H Application Details Handling References for anti-Complement Factor H antibody (ABIN951646) Images
Specificity This antibody reacts to CFH.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Immunogen KLH conjugated synthetic peptide between 751-780 amino acids from the Central region of human CFH
Isotype Ig Fraction
Plasmids, Primers & others

Target Details Complement Factor H

Product Details anti-Complement Factor H Antibody Application Details Handling References for anti-Complement Factor H antibody (ABIN951646) Images back to top
Antigen
Background This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Synonyms: CFH, H factor 1, HF, HF1, HF2
Molecular Weight 139096 Da
Gene ID 3075
NCBI Accession NP_000177
Pathways Complement System, Cellular Response to Molecule of Bacterial Origin

Application Details

Product Details anti-Complement Factor H Antibody Target Details Complement Factor H Handling References for anti-Complement Factor H antibody (ABIN951646) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Complement Factor H Antibody Target Details Complement Factor H Application Details References for anti-Complement Factor H antibody (ABIN951646) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-Complement Factor H antibody (ABIN951646)

Product Details anti-Complement Factor H Antibody Target Details Complement Factor H Application Details Handling Images back to top
Background publications

Dieterich, Hammerschmidt, Richter, Skerka, Wallich, Matuschka, Zipfel, Kraiczy: "Inadequate binding of immune regulator factor H is associated with sensitivity of Borrelia lusitaniae to human complement." in: Infection and immunity, Vol. 78, Issue 11, pp. 4467-76, 2010

Sofat, Casas, Kumari, Talmud, Ireland, Kivimaki, Marmot, Hughes, Thom, Ebrahim, Whittaker, Smeeth, Lawlor, Humphries, Hingorani: "Genetic variation in complement factor H and risk of coronary heart disease: eight new studies and a meta-analysis of around 48,000 individuals." in: Atherosclerosis, Vol. 213, Issue 1, pp. 184-90, 2010

Davila, Wright, Khor, Sim, Binder, Breunis, Inwald, Nadel, Betts, Carrol, de Groot, Hermans, Hazelzet, Emonts, Lim, Kuijpers, Martinon-Torres, Salas, Zenz, Levin, Hibberd: "Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease." in: Nature genetics, Vol. 42, Issue 9, pp. 772-6, 2010

Images

Product Details anti-Complement Factor H Antibody Target Details Complement Factor H Application Details Handling References for anti-Complement Factor H antibody (ABIN951646) back to top
Supplier Images
Immunofluorescence (IF) image for anti-Complement Factor H (CFH) (AA 751-780), (Middle Region) antibody (ABIN951646) Confocal immunofluorescent analysis of CFH Antibody (Center) with A549 cell followed ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Complement Factor H (CFH) (AA 751-780), (Middle Region) antibody (ABIN951646) CFH antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin em...
Western Blotting (WB) image for anti-Complement Factor H (CFH) (AA 751-780), (Middle Region) antibody (ABIN951646) CFH Antibody (Center) western blot analysis in K562 cell line lysates (35µg/lane).Thi...