DDR1 Products
(Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
Categories
Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011].
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Featured DDR1 Categories
DDR1 Antibodies
High quality antibodies with extensive validation data.
DDR1 ELISA Kits
Reliable ELISA kits for a wide range of species.
DDR1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DDR1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
WB, IHC (p), FACS
Validations
- (5)
Cat. No.
ABIN392014
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS, IF
Validations
- (5)
Cat. No.
ABIN391458
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, IF
Validations
- (7)
Cat. No.
ABIN3030734
Quantity
0.4 mL
Datasheet
Datasheet
Recommended DDR1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (3)
Cat. No.
ABIN5526734
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (3)
Cat. No.
ABIN5526735
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966389
Quantity
96 tests
Datasheet
Datasheet
Recommended DDR1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7274460
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7274462
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
Cat. No.
ABIN5570031
Quantity
5 μg
Datasheet
Datasheet
Latest Publications for our DDR1 products
: "Targeting of DDR1 with antibody-drug conjugates has antitumor effects in a mouse model of colon carcinoma." in: Molecular oncology, (2019) (PubMed).: "Normal activation of discoidin domain receptor 1 mutants with disulfide cross-links, insertions, or deletions in the extracellular juxtamembrane region: mechanistic implications." in: The Journal of biological chemistry, Vol. 289, Issue 19, pp. 13565-74, (2014) (PubMed).
: "Activated hair follicle stem cells and Wnt/?-catenin signaling involve in pathnogenesis of sebaceous neoplasms." in: International journal of medical sciences, Vol. 11, Issue 10, pp. 1022-8, (2014) (PubMed).
: "A unique and potent protein binding nature of liposome containing polyethylenimine and polyethylene glycol: a nondisplaceable property." in: Biotechnology and bioengineering, Vol. 108, Issue 6, pp. 1318-27, (2011) (PubMed).
: "Novel markers for differentiation of lobular and ductal invasive breast carcinomas by laser microdissection and microarray analysis." in: BMC cancer, Vol. 7, pp. 55, (2007) (PubMed).
: "Sensing extracellular matrix: an update on discoidin domain receptor function." in: Cellular signalling, Vol. 18, Issue 8, pp. 1108-16, (2006) (PubMed).
: "Professional practice solutions.... How does a healthcare organization deal with conflicting directives between HCFA regulations and Joint Commission standards when obligated to abide by both?" in: Journal of AHIMA / American Health Information Management Association, Vol. 72, Issue 7, pp. 87-8, (2005) (PubMed).
: "Discoidin domain receptor (DDR) 1 and 2: collagen-activated tyrosine kinase receptors in the cornea." in: Experimental eye research, Vol. 72, Issue 1, pp. 87-92, (2001) (PubMed).
: "Discoidin domain receptor 1 (DDR1) signaling in PC12 cells: activation of juxtamembrane domains in PDGFR/DDR/TrkA chimeric receptors." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 14, Issue 7, pp. 973-81, (2000) (PubMed).
: "Discoidin domain receptor 1 functions in axon extension of cerebellar granule neurons." in: Genes & development, Vol. 14, Issue 17, pp. 2216-28, (2000) (PubMed).
Synonyms and alternative names related to DDR1
Discoidin domain receptor (Ddr), discoidin domain receptor family, member 1 (Ddr1), discoidin domain receptor tyrosine kinase 1 (DDR1), discoidin domain receptor tyrosine kinase 1 (Ddr1), 6030432F18, AI323681, Cak, CAK, CD167, CD167a, CG9488, CG9490, CG11573, CG13984, CG13985, CG33531, CT33540, DDR, Dmel\\CG33531, Dmel_CG13984, Drd1, EDDR1, HGK2, MCK10, Nep, NEP, NTRK4, PTK3, PTK3A, PTK3D, RTK6, TRKEProtein level used designations for DDR1
- CG33531-PA
- CG33531-PB
- Ddr-PA
- Ddr-PB
- discoidin domain receptor
- CD167 antigen-like family member A
- cell adhesion kinase
- discoidin receptor tyrosine kinase
- epithelial discoidin domain receptor 1
- epithelial discoidin domain-containing receptor 1
- protein-tyrosine kinase MPK-6
- tyrosine kinase DDR
- tyrosine-protein kinase CAK
- PTK3A protein tyrosine kinase 3A
- mammary carcinoma kinase 10
- neuroepithelial tyrosine kinase
- neurotrophic tyrosine kinase, receptor, type 4
- protein-tyrosine kinase RTK-6
- discoidin domain receptor family, member 1
- neurotrophic tyrosine kinase receptor type 4
- protein-tyrosine kinase 3
- protein-tyrosine kinase PTK-3
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