DIO3 Protein (AA 37-278, Extracellular) (His tag)
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- Target See all DIO3 Proteins
- DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
- Protein Type
- Recombinant
- Protein Characteristics
- Extracellular, AA 37-278
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Origin
- Rat
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This DIO3 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- DFLCIRKHFL RRRHPDHPEP EVELNSEGEE MPPDDPPICV SDDNRLCTLA SLKAVWHGQK LDFFKQAHEG GPAPNSEVVR PDGFQSQRIL DYAQGTRPLV LNFGSCTPPF MARMSAFQRL VTKYQRDVDF LIIYIEEAHP SDGWVTTDSP YVIPQHRSLE DRVSAARVLQ QGAPGCALVL DTMANSSSSA YGAYFERLYV IQSGTIMYQG GRGPDGYQVS ELRTWLERYD EQLHGTRPRR L
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product DIO3 Protein
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Deiodinase, Iodothyronine, Type III (DIO3) (AA 43-143) protein (GST tag)
DIO3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Deiodinase, Iodothyronine, Type III (DIO3) (AA 1-143) protein (GST tag)DIO3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Deiodinase, Iodothyronine, Type III (DIO3) (AA 68-304) protein (His tag)Crystallography grade DIO3 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Deiodinase, Iodothyronine, Type III (DIO3) (AA 68-304) protein (His tag)Crystallography grade DIO3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Deiodinase, Iodothyronine, Type III (DIO3) (AA 1-304) protein (Strep Tag)Crystallography grade DIO3 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Deiodinase, Iodothyronine, Type III (DIO3) (AA 1-304) protein (Strep Tag)Crystallography grade DIO3 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Deiodinase, Iodothyronine, Type III (DIO3) (AA 37-278) protein (His tag)DIO3 Origin: Rat Host: Yeast Recombinant > 90 % ELISA
Deiodinase, Iodothyronine, Type III (DIO3) (AA 37-278), (Extracellular) protein (His tag)DIO3 Origin: Rat Host: Yeast Recombinant > 90 % SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
- Alternative Name
- IOD3 (DIO3 Products)
- Synonyms
- 5DIII Protein, DIOIII Protein, txdi3 Protein, dioiii Protein, XL-15 Protein, itdi3 Protein, D3 Protein, TXDI3 Protein, iodothyronine deiodinase 3 Protein, deiodinase, iodothyronine, type 3 Protein, deiodinase, iodothyronine, type III Protein, deiodinase, iodothyronine type III Protein, deiodinase, iodothyronine, type 3 L homeolog Protein, DIO3 Protein, dio3 Protein, Dio3 Protein, dio3.L Protein
- Background
- Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing prature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during bryological development.
- Molecular Weight
- 31.5 kDa
- UniProt
- P49897
- Pathways
- Hormone Activity
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