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Extracellular Matrix Protein 1 Products

(Extracellular Matrix Protein 1 (ECM1))
Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin. [provided by RefSeq, Jul 2008].

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Featured Extracellular Matrix Protein 1 Categories

Extracellular Matrix Protein 1 Antibodies

High quality antibodies with extensive validation data.

Extracellular Matrix Protein 1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Extracellular Matrix Protein 1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Extracellular Matrix Protein 1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, FACS, IHC (p), IHC (fro), IF (cc), IF (p)
Validations
  • (1)
  • (3)
Cat. No. ABIN673071
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application IHC, WB, IP, ICC
Validations
  • (3)
Cat. No. ABIN7434926
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN7267071
Quantity 100 μL
Datasheet Datasheet

Recommended Extracellular Matrix Protein 1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6973884
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966619
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955677
Quantity 96 tests
Datasheet Datasheet

Recommended Extracellular Matrix Protein 1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122867
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352291
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7320312
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Extracellular Matrix Protein 1 products

Philley, Kannan, Griffith, Devine, Benwill, Wallace, Brown-Elliott, Thakkar, Taskar, Fox, Alqaid, Bains, Gupta, Dasgupta: "Exosome secretome and mediated signaling in breast cancer patients with nontuberculous mycobacterial disease." in: Oncotarget, Vol. 8, Issue 11, pp. 18070-18081, (2017) (PubMed).

Lee, Nam, Oh, Lim, Kim, Lee, Yu, Ahn, Kim, Noh, Lee, Shin: "Extracellular matrix protein 1 regulates cell proliferation and trastuzumab resistance through activation of epidermal growth factor signaling." in: Breast cancer research : BCR, Vol. 16, Issue 6, pp. 479, (2015) (PubMed).

Lee, Nam, Oh, Lim, Kim, Shim, Choi, Lee, Yu, Lee, Ahn, Shin: "ECM1 regulates tumor metastasis and CSC-like property through stabilization of β-catenin." in: Oncogene, Vol. 34, Issue 50, pp. 6055-65, (2015) (PubMed).

Gao, Zhang, Ding, Chen, Hu, Jiang, Li, Chen, Wang, Ye, Zhu: "Common expression of stemness molecular markers and early cardiac transcription factors in human Wharton's jelly-derived mesenchymal stem cells and embryonic stem cells." in: Cell transplantation, Vol. 22, Issue 10, pp. 1883-900, (2014) (PubMed).

Drabovich, Dimitromanolakis, Saraon, Soosaipillai, Batruch, Mullen, Jarvi, Diamandis: "Differential diagnosis of azoospermia with proteomic biomarkers ECM1 and TEX101 quantified in seminal plasma." in: Science translational medicine, Vol. 5, Issue 212, pp. 212ra160, (2013) (PubMed).

Fry, Sinclair, Timms, Leathem, Dwek: "A targeted glycoproteomic approach identifies cadherin-5 as a novel biomarker of metastatic breast cancer." in: Cancer letters, Vol. 328, Issue 2, pp. 335-44, (2012) (PubMed).

Polosukhin, Cates, Lawson, Zaynagetdinov, Milstone, Massion, Ocak, Ware, Lee, Bowler, Kononov, Randell, Blackwell: "Bronchial secretory immunoglobulin a deficiency correlates with airway inflammation and progression of chronic obstructive pulmonary disease." in: American journal of respiratory and critical care medicine, Vol. 184, Issue 3, pp. 317-27, (2011) (PubMed).

Gologan, Acquafondata, Dhir, Sepulveda: "Polymeric immunoglobulin receptor-negative tumors represent a more aggressive type of adenocarcinomas of distal esophagus and gastroesophageal junction." in: Archives of pathology & laboratory medicine, Vol. 132, Issue 8, pp. 1295-301, (2008) (PubMed).

Tang, Tao, Yun-Liu, Sun, Geng, Jiang: "Immunocytochemical localization of secretory component in Paneth cell secretory granules-rat Paneth cells participate in acquired immunity." in: Journal of molecular histology, Vol. 36, Issue 5, pp. 331-5, (2005) (PubMed).

Fichorova, Anderson: "Differential expression of immunobiological mediators by immortalized human cervical and vaginal epithelial cells." in: Biology of reproduction, Vol. 60, Issue 2, pp. 508-14, (1999) (PubMed).

Synonyms and alternative names related to Extracellular Matrix Protein 1

extracellular matrix protein 1 (ECM1), polymeric immunoglobulin receptor (PIGR), multimerin 1 (MMRN1), polymeric immunoglobulin receptor (Pigr), extracellular matrix protein 1 (Ecm1), AI663821, ECM, EMILIN4, GPIa*, MMRN, p85, pIgA-R, RNPIGR2, URBWD

Protein level used designations for Extracellular Matrix Protein 1

  • secretory component p85
  • hepatocellular carcinoma associated protein TB6
  • hepatocellular carcinoma-associated protein TB6
  • poly-Ig receptor
  • EMILIN-4
  • elastin microfibril interface located protein 4
  • elastin microfibril interfacer 4
  • endothelial cell multimerin
  • glycoprotein Ia*
  • multimerin-1
  • extracellular matrix protein 1
  • polymeric IgA receptor
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