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FAF2 Products

(Fas Associated Factor Family Member 2 (FAF2))

Categories

The protein encoded by this gene is highly expressed in peripheral blood of patients with atopic dermatitis (AD), compared to normal individuals. It may play a role in regulating the resistance to apoptosis that is observed in T cells and eosinophils of AD patients. [provided by RefSeq, Jul 2008].

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Featured FAF2 Categories

FAF2 Antibodies

High quality antibodies with extensive validation data.

FAF2 ELISA Kits

Reliable ELISA kits for a wide range of species.

FAF2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FAF2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (3)
  • (3)
Cat. No. ABIN525021
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN185060
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (3)
Cat. No. ABIN2856552
Quantity 100 μL
Datasheet Datasheet

Recommended FAF2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966649
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6204137
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1133012
Quantity 96 tests
Datasheet Datasheet

Recommended FAF2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1353374
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
Cat. No. ABIN3121795
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN3080080
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our FAF2 products

Xia, Yan, Huang, Liu, Liu, Huang: "Pathogenic mutation of UBQLN2 impairs its interaction with UBXD8 and disrupts endoplasmic reticulum-associated protein degradation." in: Journal of neurochemistry, Vol. 129, Issue 1, pp. 99-106, (2014) (PubMed).

Jo, Hartman, DeBose-Boyd: "Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet-associated endoplasmic reticulum membranes." in: Molecular biology of the cell, Vol. 24, Issue 3, pp. 169-83, (2013) (PubMed).

Beilstein, Bouchoux, Rousset, Demignot: "Proteomic analysis of lipid droplets from Caco-2/TC7 enterocytes identifies novel modulators of lipid secretion." in: PLoS ONE, Vol. 8, Issue 1, pp. e53017, (2013) (PubMed).

Xu, Liu, Lee, Ye: "A ubiquitin-like domain recruits an oligomeric chaperone to a retrotranslocation complex in endoplasmic reticulum-associated degradation." in: The Journal of biological chemistry, Vol. 288, Issue 25, pp. 18068-76, (2013) (PubMed).

Suzuki, Otsuka, Ohsaki, Cheng, Taniguchi, Hashimoto, Taniguchi, Fujimoto: "Derlin-1 and UBXD8 are engaged in dislocation and degradation of lipidated ApoB-100 at lipid droplets." in: Molecular biology of the cell, Vol. 23, Issue 5, pp. 800-10, (2012) (PubMed).

Gong, Traganos, Darzynkiewicz: "Expression of cyclins-B and cyclins-e in individual molt-4 cells and in stimulated human-lymphocytes during their progression through the cell-cycle." in: International journal of oncology, Vol. 3, Issue 6, pp. 1037-42, (2011) (PubMed).

Jo, Lee, Sguigna, DeBose-Boyd: "Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 51, pp. 20503-8, (2011) (PubMed).

Hartman, Liu, Zehmer, Luby-Phelps, Jo, Anderson, DeBose-Boyd: "Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from endoplasmic reticulum membranes into the cytosol through a subcellular compartment resembling lipid droplets." in: The Journal of biological chemistry, Vol. 285, Issue 25, pp. 19288-98, (2010) (PubMed).

Lee, Zhang, Feramisco, Gong, Ye: "Unsaturated fatty acids inhibit proteasomal degradation of Insig-1 at a postubiquitination step." in: The Journal of biological chemistry, Vol. 283, Issue 48, pp. 33772-83, (2008) (PubMed).

Imai, Nakada, Hashida, Sugita, Tanaka, Tsujimoto, Matsumoto, Akasawa, Saito, Oshida: "Cloning and characterization of the highly expressed ETEA gene from blood cells of atopic dermatitis patients." in: Biochemical and biophysical research communications, Vol. 297, Issue 5, pp. 1282-90, (2002) (PubMed).

Synonyms and alternative names related to FAF2

Fas associated factor family member 2 (FAF2), Fas associated factor family member 2 (Faf2), Fas associated factor family member 2 S homeolog (faf2.S), 2210404D11Rik, 2210404d11rik, AI462440, ETEA, etea, FAF2, mKIAA0887, RGD1306577, UBX8, UBXD8, Ubxd8, ubxd8, UBXN3B, ubxn3b

Protein level used designations for FAF2

  • Fas associated factor family member 2
  • UBX domain containing 8
  • FAS-associated factor 2-like
  • FAS-associated factor 2
  • UBX domain protein 3B
  • UBX domain-containing protein 3B
  • UBX domain-containing protein 8
  • expressed in T-cells and eosinophils in atopic dermatitis
  • protein expressed in T-cells and eosinophils in atopic dermatitis
  • FAS-associated factor 2-A
  • UBX domain-containing protein 8-A
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