FLI1 Products
(Friend Leukemia Virus Integration 1 (FLI1))
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This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11\;22)(q24\;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4\;11)(q21\;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].
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Featured FLI1 Categories
FLI1 Antibodies
High quality antibodies with extensive validation data.
FLI1 ELISA Kits
Reliable ELISA kits for a wide range of species.
FLI1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FLI1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS
Validations
- (6)
Cat. No.
ABIN7193672
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, RNAi
Validations
- (5)
Cat. No.
ABIN515745
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7153171
Quantity
100 μg
Datasheet
Datasheet
Recommended FLI1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1381141
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative DNA-Binding ELISA
Validations
Cat. No.
ABIN5648544
Quantity
96 tests
Datasheet
Datasheet
Recommended FLI1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123005
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1354154
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3080222
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our FLI1 products
: "Endothelial Cell Infection by Guinea Pig Cytomegalovirus Is a Lytic or Persistent Infection Depending on Tissue Origin but Requires Viral Pentamer Complex and pp65 Tegument Protein." in: Journal of virology, Vol. 96, Issue 17, pp. e0083122, (2022) (PubMed).: "Combinatorial Drug Screening Identifies Ewing Sarcoma-specific Sensitivities." in: Molecular cancer therapeutics, Vol. 16, Issue 1, pp. 88-101, (2017) (PubMed).
: "Ciprofloxacin has antifibrotic effects in scleroderma fibroblasts via downregulation of Dnmt1 and upregulation of Fli1." in: International journal of molecular medicine, Vol. 30, Issue 6, pp. 1473-80, (2012) (PubMed).
: "A novel oncogenic mechanism in Ewing sarcoma involving IGF pathway targeting by EWS/Fli1-regulated microRNAs." in: Oncogene, Vol. 30, Issue 49, pp. 4910-20, (2011) (PubMed).
: "DNA-binding and transcriptional activation properties of the EWS-FLI-1 fusion protein resulting from the t(11;22) translocation in Ewing sarcoma." in: Molecular and cellular biology, Vol. 14, Issue 5, pp. 3230-41, (1994) (PubMed).
: "The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1." in: Molecular and cellular biology, Vol. 13, Issue 12, pp. 7393-8, (1994) (PubMed).
Synonyms and alternative names related to FLI1
Fli-1 proto-oncogene, ETS transcription factor (FLI1), Fli-1 proto-oncogene, ETS transcription factor (Fli1), Fli-1 proto-oncogene, ETS transcription factor S homeolog (fli1.S), Fli-1 proto-oncogene, ETS transcription factor (fli1), Friend leukemia integration 1 (Fli1), Fli-1 proto-oncogene, ETS transcription factor a (fli1a), Fli-1 proto-oncogene, ETS transcription factor L homeolog (fli1.L), cb855, EWSR2, fli, fli-1, Fli-1, FLI1, fli1, MGC121593, SIC-1, Sic1, wu:fc45b11, Xfli, Xfli-1, Xfli1, xlfliProtein level used designations for FLI1
- Ewing sarcoma breakpoint region 2
- Friend leukemia integration 1 transcription factor
- Friend leukemia virus integration 1
- proto-oncogene Fli-1
- transcription factor ERGB
- fli-1 proto-oncogene
- friend leukemia integration 1 transcription factor-like
- Friend leukemia integration 1 transcription factor-like
- retroviral integration site protein Fli-1
- retroviral integration site protein Fli-1 homolog
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