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FPGT Products

(Fucose-1-Phosphate Guanylyltransferase (FPGT))

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L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose\; the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream TNNI3 interacting kinase (TNNI3K) gene. [provided by RefSeq, Dec 2010].

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Featured FPGT Categories

FPGT Antibodies

High quality antibodies with extensive validation data.

FPGT Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FPGT Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (4)
Cat. No. ABIN948733
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application ICC, IHC, WB
Validations
  • (3)
Cat. No. ABIN5013573
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC (p), WB
Validations
  • (2)
Cat. No. ABIN2855758
Quantity 100 μL
Datasheet Datasheet

Recommended FPGT ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6222823
Quantity 96 tests
Datasheet Datasheet

Recommended FPGT Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3131215
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3080408
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354411
Quantity 10 μg
Datasheet Datasheet

Synonyms and alternative names related to FPGT

fucose-1-phosphate guanylyltransferase (fpgt), fucose-1-phosphate guanylyltransferase (FPGT), fucose-1-phosphate guanylyltransferase L homeolog (fpgt.L), fucose-1-phosphate guanylyltransferase (Fpgt), 1700016E03Rik, DDBDRAFT_0186414, DDBDRAFT_0233144, DDB_0186414, DDB_0233144, DKFZp459M111, FPGT, fpgt, GFPP, zgc:110694

Protein level used designations for FPGT

  • fucose-1-phosphate guanylyltransferase
  • Fucose-1-phosphate guanylyltransferase
  • fucose-1-phosphate guanylyltransferase-like
  • GDP-L-fucose diphosphorylase
  • GDP-beta-L-fucose pyrophosphorylase
  • fucose-1-phosphate guanyltransferase
  • gdp-L-fucose pyrophosphorylase
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