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FRS2 Proteins

(Fibroblast Growth Factor Receptor Substrate 2 (FRS2))
Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3- kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.

11 results :

FRS2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Pubmed 2 references
Catalog No. ABIN1354441
 
FRS2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Catalog No. ABIN7122957
 
FRS2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Catalog No. ABIN1354439
 
FRS2 Origin: Human Host: Escherichia coli (E. coli) Recombinant WB, SDS, ELISA
Catalog No. ABIN7577069
 
FRS2 Origin: Human Host: Escherichia coli (E. coli) Recombinant WB, SDS, ELISA
Catalog No. ABIN7577068
 
FRS2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
Catalog No. ABIN7405370
 
FRS2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
Catalog No. ABIN7414207
 
FRS2 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
Catalog No. ABIN7405534
 
FRS2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2721422
 
FRS2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Catalog No. ABIN3009430
 
FRS2 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Catalog No. ABIN3009429
 
  • Type Protein
    • Protein
  • Application
    • Western Blotting (WB)
    • ELISA
    • SDS-PAGE (SDS)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Immunoprecipitation (IP)
    • Antibody Production (AbP)
    • Standard (STD)
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Images available
  • Carrier free only
  • Host
    • Escherichia coli (E. coli)
    • Wheat germ
    • HEK-293 Cells
  • Binding Specificity
    • AA 268-453
    • AA 1-341
    • AA 1-512
    • AA 100-304
    • AA 239-449
    • Transcript Variant 1
  • Conjugate
    • His tag
    • GST tag
    • Un-conjugated
    • His-IF2DI Tag
    • His-SUMO Tag
    • Myc-DYKDDDDK Tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Supplier
    • antibodies-online
    • Abbexa
    • OriGene

Latest Publications for our FRS2 Proteins

Krejci, Salazar, Goodridge, Kashiwada, Schibler, Jelinkova, Thompson, Wilcox: "STAT1 and STAT3 do not participate in FGF-mediated growth arrest in chondrocytes." in: Journal of cell science, Vol. 121, Issue Pt 3, pp. 272-81, (2008) (PubMed).

Krejci, Masri, Salazar, Farrington-Rock, Prats, Thompson, Wilcox: "Bisindolylmaleimide I suppresses fibroblast growth factor-mediated activation of Erk MAP kinase in chondrocytes by preventing Shp2 association with the Frs2 and Gab1 adaptor proteins." in: The Journal of biological chemistry, Vol. 282, Issue 5, pp. 2929-36, (2007) (PubMed).

Aliases for FRS2 Proteins

fibroblast growth factor receptor substrate 2 (FRS2) Proteins
fibroblast growth factor receptor substrate 2b (frs2b) Proteins
fibroblast growth factor receptor substrate 2 (Frs2) Proteins
4732458E18 Proteins
C330018A15Rik Proteins
frs2 Proteins
FRS2A Proteins
FRS2alpha Proteins
Frs2alpha Proteins
SNT Proteins
SNT-1 Proteins
SNT1 Proteins
wu:fd21h10 Proteins
zgc:91973 Proteins
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