This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
custom-made
FTH1
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
FTH1
Origin: Human
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
FTH1
Origin: Mouse
Host: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
Catalog No. ABIN3132682
starts at
$20,480.57
Plus shipping costs $50.00, if applicable $20.00 dry ice
custom-made
FTH1
Origin: Human
Host: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
Catalog No. ABIN3080261
starts at
$20,480.57
Plus shipping costs $50.00, if applicable $20.00 dry ice
Inokura, Fujiwara, Saito, Iino, Hatta, Okitsu, Fukuhara, Onishi, Ishizawa, Shimoda, Harigae: "Impact of TET2 deficiency on iron metabolism in erythroblasts." in: Experimental hematology, Vol. 49, pp. 56-67.e5, (2017) (PubMed).
Chou, Gatti, Fuller, Concannon, Wong, Chada, Davis, Salser: "Structure and expression of ferritin genes in a human promyelocytic cell line that differentiates in vitro." in: Molecular and cellular biology, Vol. 6, Issue 2, pp. 566-73, (1987) (PubMed).
Boyd, Vecoli, Belcher, Jain, Drysdale: "Structural and functional relationships of human ferritin H and L chains deduced from cDNA clones." in: The Journal of biological chemistry, Vol. 260, Issue 21, pp. 11755-61, (1985) (PubMed).
Costanzo, Santoro, Colantuoni, Bensi, Raugei, Romano, Cortese: "Cloning and sequencing of a full length cDNA coding for a human apoferritin H chain: evidence for a multigene family." in: The EMBO journal, Vol. 3, Issue 1, pp. 23-7, (1984) (PubMed).
Aliases for FTH1 Proteins
ferritin heavy chain 1 (FTH1) Proteins ferritin, heavy polypeptide 1 L homeolog (fth1.L) Proteins ferritin, heavy polypeptide 1 S homeolog (fth1.S) Proteins ferritin heavy polypeptide 1 (Fth1) Proteins ferritin heavy chain 1 (Fth1) Proteins ferritin, heavy polypeptide 1a (fth1a) Proteins ferritin (EAMY_RS19690) Proteins ferritin, heavy polypeptide 1 (fth1) Proteins tudor domain containing 9 (TDRD9) Proteins ferritin, heavy polypeptide 1 (FTH1) Proteins ferritin, heavy polypeptide 1 a (fth1a) Proteins apoferritin Proteins fb06g09 Proteins ferritin Proteins FHC Proteins fhc Proteins FTH Proteins fth Proteins Fth Proteins fth1 Proteins fth1b Proteins FTHL6 Proteins fthl6 Proteins ftn-2 Proteins HFt Proteins hm:zeh1145 Proteins MFH Proteins PIG15 Proteins pig15 Proteins PLIF Proteins plif Proteins wu:fb06g09 Proteins wu:fq18c10 Proteins zeh1145 Proteins