HCN4 Products
(Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 4 (HCN4))
Categories
This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15. [provided by RefSeq, Oct 2008].
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Featured HCN4 Categories
HCN4 Antibodies
High quality antibodies with extensive validation data.
HCN4 ELISA Kits
Reliable ELISA kits for a wide range of species.
HCN4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HCN4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, IHC, IF, ICC, FACS, AA
Validations
- (4)
Cat. No.
ABIN361779
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IF, ICC, FACS, AA
Validations
- (4)
Cat. No.
ABIN2482538
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IF, ICC, FACS, AA
Validations
- (4)
Cat. No.
ABIN2482537
Quantity
100 μg
Datasheet
Datasheet
Recommended HCN4 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967499
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956642
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4883177
Quantity
96 tests
Datasheet
Datasheet
Recommended HCN4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123394
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306433
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3081282
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our HCN4 products
: "Fixation strategies for retinal immunohistochemistry." in: Progress in retinal and eye research, Vol. 48, pp. 181-202, (2015) (PubMed).: "Association between reversal in the expression of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel and age-related atrial fibrillation." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 20, pp. 2292-7, (2014) (PubMed).
: "Cardiac arrhythmia induced by genetic silencing of 'funny' (f) channels is rescued by GIRK4 inactivation." in: Nature communications, Vol. 5, pp. 4664, (2014) (PubMed).
: "Induction of diverse cardiac cell types by reprogramming fibroblasts with cardiac transcription factors." in: Development (Cambridge, England), Vol. 141, Issue 22, pp. 4267-78, (2014) (PubMed).
: "HCN4 subunit expression in fast-spiking interneurons of the rat spinal cord and hippocampus." in: Neuroscience, Vol. 237, pp. 7-18, (2013) (PubMed).
: "Directional summation in non-direction selective retinal ganglion cells." in: PLoS computational biology, Vol. 9, Issue 3, pp. e1002969, (2013) (PubMed).
: "Testosterone enhances cardiomyogenesis in stem cells and recruits the androgen receptor to the MEF2C and HCN4 genes." in: Journal of molecular and cellular cardiology, Vol. 60, pp. 164-71, (2013) (PubMed).
: "HCN1 subunits contribute to the kinetics of I(h) in neonatal cortical plate neurons." in: Developmental neurobiology, Vol. 73, Issue 10, pp. 785-97, (2013) (PubMed).
: "Chronic atrial fibrillation alters the functional properties of If in the human atrium." in: Journal of cardiovascular electrophysiology, Vol. 24, Issue 12, pp. 1391-400, (2013) (PubMed).
: "Network state-dependent inhibition of identified hippocampal CA3 axo-axonic cells in vivo." in: Nature neuroscience, Vol. 16, Issue 12, pp. 1802-11, (2013) (PubMed).
Synonyms and alternative names related to HCN4
hyperpolarization activated cyclic nucleotide gated potassium channel 4 (HCN4), hyperpolarization activated cyclic nucleotide gated potassium channel 4 (hcn4), hyperpolarization activated cyclic nucleotide-gated potassium channel 4 (Hcn4), hyperpolarization-activated, cyclic nucleotide-gated K+ 4 (Hcn4), Bcng3, HAC4, Hcn3, SSS2Protein level used designations for HCN4
- hyperpolarization activated cyclic nucleotide-gated potassium channel 4
- hyperpolarization activated cyclic nucleotide-gated cation channel 4
- potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
- hyperpolarization-activated, cyclic nucleotide-gated K+ 4
- HAC-4
- hyperpolarization activated cation channel
- hyperpolarization-activated cation channel 4
- BCNG-3
- brain cyclic nucleotide-gated channel 3
- hyperpolarization-activated, cyclic nucleotide-gated K+ 3
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