(Host Cell Proteins (HCP))
In biopharmaceutic manufacturing the term host cell proteins (HCPs) clusters proteins impurities derived from the host organism which are present during in the manufacturing process of monoclonal antibodies, antibody-drug-conjugates, therapeutic proteins, and other protein-based biopharmaceuticals.
Quantitation and removal of HCPs in the final drug product to acceptable low levels is essential. Impurities accompanied with recombinant biotherapeutics can significantly affect drug efficacy and cause immunogenicity.
Custom HCP Antibody Services
Are you interested in a custom made antibody and assays tailored for your needs to screen your biological production process for HCP impurities? In that case we have the right program for you at hand.
Benefit from the combined expertise of antibodies-online and our partner Rockland Immunochemicals, Inc. (Rockland).. Leverage Rockland’s 15+ years of success generating custom polyclonal HCP antibodies to keep your biopharmaceutical development program meeting deadlines and moving efficiently.
Our comprehensive, fully customizable services cover all aspects of anti-HCP antibody generation, from antigen preparation and assay development to documentation and manufacturing.Learn more about our Custom HCP Antibody Services
antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.
Recommended HCP Antibodies
Recommended HCP Proteins
Latest Publications for our HCP products: "Polyclonal F(ab')2 fragments of equine antibodies raised against the spike protein neutralize SARS-CoV-2 variants with high potency. ..." in: iScience, Vol. 24, Issue 11, pp. 103315, (2021) (PubMed).
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