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IL-1 beta Proteins

(Interleukin 1, beta (IL1B))
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008].

92 results

IL1B Origin: Pig Host: Escherichia coli (E. coli) Recombinant > 97 % SDS, WB, Imm, PC
Catalog No. ABIN7391024
 
IL1B Origin: Cow Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Catalog No. ABIN7391003
 
IL1B Origin: Sheep Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Catalog No. ABIN7414972
 
IL1B Origin: Cow Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Catalog No. ABIN7416367
 
IL1B Origin: Human Host: Escherichia coli (E. coli) Recombinant >98 % (SDS-PAGE)
Catalog No. ABIN7278697
 
IL1B Origin: Human Host: Escherichia coli (E. coli) Recombinant >98 % (SDS-PAGE)
Catalog No. ABIN7566204
 
IL1B Origin: Zebrafish (Danio rerio) Host: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC
Catalog No. ABIN7424437
 
IL1B Origin: Chicken Host: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC
Catalog No. ABIN7391012
 
IL1B Origin: Dog Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Catalog No. ABIN7391006
 
IL1B Origin: Horse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Catalog No. ABIN7391009
 
IL1B Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Catalog No. ABIN7196350
 
IL1B Origin: Rat Host: HEK-293 Cells Recombinant
Catalog No. ABIN7520134
 
IL1B Origin: Dog Host: Escherichia coli (E. coli) Recombinant > 95% by SDS-PAGE SDS, AcA Active
Catalog No. ABIN7596223
 
Rockland 012-001-301-0010 IL1B Origin: Rat Host: Escherichia coli (E. coli) Recombinant 97,00% SDS
Catalog No. ABIN6699996
Rockland Original
Rockland 010-001-319 IL1B Origin: Mouse Host: Escherichia coli (E. coli) Recombinant 97,00% SDS
Catalog No. ABIN6699989
Rockland Original
Rockland 009-001-301 IL1B Origin: Human Host: Escherichia coli (E. coli) Recombinant 97,00% SDS
Catalog No. ABIN6699988
Rockland Original
IL1B Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5713080
 
IL1B Origin: Rabbit Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Catalog No. ABIN3010120
 
IL1B Origin: Guinea Pig Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Catalog No. ABIN3010116
 
IL1B Origin: Sheep Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5709739
 
  • Type Protein
    • Protein
  • Application
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • ELISA
    • Immunogen (Imm)
    • Positive Control (PC)
    • Activity Assay (AcA)
    • Immunoprecipitation (IP)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Biochemical Assay (BCA)
    • Cell Culture (CC)
    • Functional Studies (Func)
    • Antibody Production (AbP)
    • Standard (STD)
  • Reactivity
    • Human
    • Mouse
    • Rat
    • Dog
    • Chicken
    • Cow
    • Horse
    • Pig
    • Rabbit
    • Guinea Pig
    • Rhesus Monkey
    • Sheep
    • Cynomolgus
    • Goat
    • Beluga
    • Cat
    • Llama
    • Macaca nemestrina
    • Monkey
    • Red Deer
    • White-eyelid mangabey (Cercocebus)
    • Zebrafish (Danio rerio)
  • Cited in publications
  • Images available
  • Preservative free only
  • Carrier free only
  • Host
    • Escherichia coli (E. coli)
    • Yeast
    • HEK-293 Cells
    • CHO Cells
    • Wheat germ
  • Binding Specificity
    • AA 117-269
    • AA 114-266
    • AA 117-268
    • AA 118-269
    • AA 115-266
    • AA 115-267
    • AA 1-266
    • AA 116-268
    • AA 1-269
    • AA 1-273
    • AA 103-260
    • AA 106-267
    • AA 109-251
    • AA 110-263
    • AA 114-265
    • AA 116-267
    • AA 118-268
    • AA 119-268
    • AA 13-242
    • AA 170-269
    • AA 63-247
    • AA 95-262
    • full length
    • partial
  • Conjugate
    • His tag
    • Un-conjugated
    • GST tag
    • Fc Tag
    • His-Avi Tag,Biotin
    • His tag,GST tag
    • His-Avi Tag
    • Myc-DYKDDDDK Tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biological Activity
    • Biologically Active
  • Grade
    • Animal-Free
    • MALS verified
  • Supplier
    • antibodies-online
    • CUSABIO
    • Rockland
    • Abbexa
    • ACROBiosystems
    • Cloud-Clone
    • ITSI-Biosciences
    • Signalway
    • OriGene

Latest Publications for our IL-1 beta Proteins

Shao, Fang, Dang, Xue, Zhang, Li, Qiao, Cao, Zhuang, Shen, Zhang, Qiao, Li, Gudjonsson, Wang: "Neutrophil Extracellular Traps Promote Inflammatory Responses in Psoriasis via Activating Epidermal TLR4/IL-36R Crosstalk." in: Frontiers in immunology, Vol. 10, pp. 746, (2020) (PubMed).

Luo, Huang, He, Liu, Chen, Liu, Mi, Li, Sun, Li, Xiang, Su: "Inflammatory Human Umbilical Cord-Derived Mesenchymal Stem Cells Promote Stem Cell-Like Characteristics of Cancer Cells in an IL-1β-Dependent Manner." in: BioMed research international, Vol. 2018, pp. 7096707, (2018) (PubMed).

Hollborn, Vogler, Reichenbach, Wiedemann, Bringmann, Kohen: "Regulation of the hyperosmotic induction of aquaporin 5 and VEGF in retinal pigment epithelial cells: involvement of NFAT5." in: Molecular vision, Vol. 21, pp. 360-77, (2015) (PubMed).

Ubertini, Norelli, DArcangelo, Gurtner, Cesareo, Baldari, Gentileschi, Piaggio, Nisticò, Soddu, Facchiano, Bossi: "Mutant p53 gains new function in promoting inflammatory signals by repression of the secreted interleukin-1 receptor antagonist." in: Oncogene, Vol. 34, Issue 19, pp. 2493-504, (2015) (PubMed).

von Burg, Chappaz, Baerenwaldt, Horvath, Bose Dasgupta, Ashok, Pieters, Tacchini-Cottier, Rolink, Acha-Orbea, Finke: "Activated group 3 innate lymphoid cells promote T-cell-mediated immune responses." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 35, pp. 12835-40, (2014) (PubMed).

Nikolakopoulou, Dutta, Chen, Miller, Trapp: "Activated microglia enhance neurogenesis via trypsinogen secretion." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 21, pp. 8714-9, (2013) (PubMed).

Kahlenberg, Thacker, Berthier, Cohen, Kretzler, Kaplan: "Inflammasome activation of IL-18 results in endothelial progenitor cell dysfunction in systemic lupus erythematosus." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 11, pp. 6143-56, (2011) (PubMed).

Zhang, Bennett, Verkman: "Ex vivo spinal cord slice model of neuromyelitis optica reveals novel immunopathogenic mechanisms." in: Annals of neurology, Vol. 70, Issue 6, pp. 943-54, (2011) (PubMed).

Tiwari, Wang, Brochetta, Ke, Vita, Qi, Rivera, Soranzo, Zabucchi, Hong, Blank: "VAMP-8 segregates mast cell-preformed mediator exocytosis from cytokine trafficking pathways." in: Blood, Vol. 111, Issue 7, pp. 3665-74, (2008) (PubMed).

Yang, Poon, Luo, Cheung, Ho, Lo, Fan: "Up-regulation of vascular endothelial growth factor (VEGF) in small-for-size liver grafts enhances macrophage activities through VEGF receptor 2-dependent pathway." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 4, pp. 2507-15, (2004) (PubMed).

Aliases for IL-1 beta Proteins

interleukin 1 beta (IL1B) Proteins
interleukin 1, beta (IL1B) Proteins
interleukin 1, beta (il1b) Proteins
interleukin 1 beta (Il1b) Proteins
IL-1 Proteins
IL-1 beta Proteins
IL-1B Proteins
Il-1b Proteins
IL-1b Proteins
IL-1BETA Proteins
IL-1beta Proteins
il1-b Proteins
IL1-BETA Proteins
IL1B Proteins
IL1beta Proteins
IL1F2 Proteins
zgc:111873 Proteins
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