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IL-10 Proteins

(Interleukin 10 (IL10))
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011].

94 results

IL10 Origin: Horse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Catalog No. ABIN7387445
-15% Promotion 2026
$744.59
$875.99
save $131.40 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
IL10 Origin: Chicken Host: Escherichia coli (E. coli) Recombinant > 97 % SDS, WB, Imm, PC
Catalog No. ABIN7387448
-15% Promotion 2026
$747.15
$879.00
save $131.85 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
IL10 Origin: Zebrafish (Danio rerio) Host: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC
Catalog No. ABIN7423036
-15% Promotion 2026
$749.70
$882.00
save $132.30 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
IL10 Origin: Rabbit Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Catalog No. ABIN7387466
-15% Promotion 2026
$804.18
$946.10
save $141.92 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
IL10 Origin: Pig Host: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC
Catalog No. ABIN7387460
-15% Promotion 2026
$883.35
$1,039.24
save $155.89 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
IL10 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95 % SDS, AcA Active
Catalog No. ABIN7677106
-15% Promotion 2026
$1,016.73
$1,196.15
save $179.42 (-15 %)
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
IL10 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % Inactive
Catalog No. ABIN7669011
-15% Promotion 2026
$1,813.56
$2,133.60
save $320.04 (-15 %)
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
 
IL10 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % Inactive
Catalog No. ABIN7669005
-15% Promotion 2026
$1,813.56
$2,133.60
save $320.04 (-15 %)
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
 
IL10 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % Inactive
Catalog No. ABIN7669010
-15% Promotion 2026
$1,813.56
$2,133.60
save $320.04 (-15 %)
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
 
IL10 Origin: Human Host: Mammalian Cells Recombinant > 90 % Inactive
Catalog No. ABIN7669006
-15% Promotion 2026
$1,813.56
$2,133.60
save $320.04 (-15 %)
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
 
IL10 Origin: Pig Host: Escherichia coli (E. coli) Recombinant > 95 % Inactive
Catalog No. ABIN7669009
-15% Promotion 2026
$1,813.56
$2,133.60
save $320.04 (-15 %)
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
 
IL10 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 90 % Inactive
Catalog No. ABIN7669008
-15% Promotion 2026
$1,813.56
$2,133.60
save $320.04 (-15 %)
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
 
IL10 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % Inactive
Catalog No. ABIN7669007
-15% Promotion 2026
$1,813.56
$2,133.60
save $320.04 (-15 %)
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
 
IL10 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5712490
$501.60
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Will be delivered in 11 Business Days
 
IL10 Origin: Mouse Host: HEK-293 Cells Recombinant >92 % as determined by SDS-PAGE.
Catalog No. ABIN2870745
$520.92
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 2 to 3 Business Days
 
IL10 Origin: Human Host: HEK-293 Cells > 97 % AcA, CC Active
Catalog No. ABIN6239730
$837.00
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 15 to 18 Business Days
 
IL10 Origin: Sheep Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN7479378
$1,090.32
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 60 to 71 Business Days
 
IL10 Origin: Cow Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN7478907
$1,090.32
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 60 to 71 Business Days
 
IL10 Origin: Rhesus Monkey Host: Yeast Recombinant > 90 % SDS
Catalog No. ABIN5713542
$908.60
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 11 Business Days
 
IL10 Origin: Cow Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Catalog No. ABIN3010149
$919.26
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 10 to 18 Business Days
 
  • Type Protein
    • Protein
  • Application
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Activity Assay (AcA)
    • Biochemical Assay (BCA)
    • Cell Culture (CC)
    • Functional Studies (Func)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Immunoprecipitation (IP)
    • Standard (STD)
  • Reactivity
    • Human
    • Mouse
    • Rat
    • Pig
    • Chicken
    • Rabbit
    • Cow
    • Dog
    • Cynomolgus
    • Goat
    • Guinea Pig
    • Horse
    • Rhesus Monkey
    • Baboon
    • Callithrix jacchus
    • Cat
    • Chimpanzee
    • Fox
    • Hamster
    • Llama
    • Macaca nemestrina
    • Marmota monax
    • Monkey
    • Orcinus orca
    • Red Deer
    • Sheep
    • Squirrel Monkey
    • White-eyelid mangabey (Cercocebus)
    • Zebrafish (Danio rerio)
  • Images available
  • Preservative free only
  • Carrier free only
  • Host
    • Escherichia coli (E. coli)
    • Yeast
    • HEK-293 Cells
    • CHO Cells
    • Mammalian Cells
    • Bacteria
    • Baculovirus infected Insect Cells
    • Human Cells
    • Wheat germ
  • Binding Specificity
    • AA 19-178
    • AA 1-178
    • AA 19-175
    • AA 22-175
    • AA 20-179
    • full length
    • partial
    • AA 17-174
    • AA 19-164
    • AA 20-177
    • AA 20-181
    • AA 21-181
    • AA 22-178
    • AA 23-180
  • Conjugate
    • His tag
    • Un-conjugated
    • GST tag
    • His tag,GST tag
    • Fc Tag
    • TRX tag
    • His-Avi Tag
    • His-Avi Tag,Biotin
    • Myc-DYKDDDDK Tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biological Activity
    • Biologically Active
    • Biologically Inactive
  • Grade
    • Animal-Free
  • Supplier
    • antibodies-online
    • CUSABIO
    • Abbexa
    • Rockland
    • ProSci
    • Signalway
    • ACROBiosystems
    • Cloud-Clone
    • ITSI-Biosciences
    • OriGene
    • ProteoGenix

Latest Publications for our IL-10 Proteins

Phadnis-Moghe, Crawford, Kaminski: "Suppression of human B cell activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin involves altered regulation of B cell lymphoma-6." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 144, Issue 1, pp. 39-50, (2015) (PubMed).

Larson, Hübner, Torrero, Morris, Brankin, Swierczewski, Davies, Vonakis, Mitre: "Chronic helminth infection reduces basophil responsiveness in an IL-10-dependent manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 9, pp. 4188-99, (2012) (PubMed).

Yang, Hirose, Takahashi, Kawakatsu, Takaiwa: "Recombinant protein yield in rice seed is enhanced by specific suppression of endogenous seed proteins at the same deposit site." in: Plant biotechnology journal, Vol. 10, Issue 9, pp. 1035-45, (2012) (PubMed).

Del Galdo, Wermuth, Addya, Fortina, Jimenez et al.: "NF?B activation and stimulation of chemokine production in normal human macrophages by the gadolinium-based magnetic resonance contrast agent Omniscan: possible role in the pathogenesis of ..." in: Annals of the rheumatic diseases, Vol. 69, Issue 11, pp. 2024-33, (2010) (PubMed).

van der Vliet, Wang, Yue, Koon, Balk, Exley: "Circulating myeloid dendritic cells of advanced cancer patients result in reduced activation and a biased cytokine profile in invariant NKT cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 11, pp. 7287-93, (2008) (PubMed).

Prussin, Metcalfe: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, (1996) (PubMed).

Schlaak, Schmitt, Hüls, Meyer zum Büschenfelde, Fleischer: "A sensitive and specific bioassay for the detection of human interleukin-10." in: Journal of immunological methods, Vol. 168, Issue 1, pp. 49-54, (1994) (PubMed).

Feng, Tang, Chang, Wilson: "Molecular cloning of rat cytokine synthesis inhibitory factor (IL-10) cDNA and expression in spleen and macrophages." in: Biochemical and biophysical research communications, Vol. 192, Issue 2, pp. 452-8, (1993) (PubMed).

Howard, OGarra, Ishida, de Waal Malefyt, de Vries: "Biological properties of interleukin 10." in: Journal of clinical immunology, Vol. 12, Issue 4, pp. 239-47, (1992) (PubMed).

Vieira, de Waal-Malefyt, Dang, Johnson, Kastelein, Fiorentino, deVries, Roncarolo, Mosmann, Moore: "Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 4, pp. 1172-6, (1991) (PubMed).

Aliases for IL-10 Proteins

interleukin 10 (IL10) Proteins
interleukin 10 (Il10) Proteins
CSIF Proteins
GVHDS Proteins
IL-10 Proteins
Il-10 Proteins
IL10A Proteins
IL10X Proteins
TGIF Proteins
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