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IL-10 Proteins

(Interleukin 10 (IL10))
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011].

Active filters:

  • Target: IL-10 (IL10)
  • Protein
Catalog no. Product Reactivity Host / Clonality Application Price & lead time
ABIN8128279
IL-10 Protein (AA 19-178) IL10 · Protein Cow HEK-293F Cells
  • AcA (Activity Assay: Listed application)
  • CC (Cell Culture: Listed application)
$1,002.18 View price
  • 50 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN8128280
IL-10 Protein (AA 19-178) IL10 · Protein Horse HEK-293F Cells
  • AcA (Activity Assay: Listed application)
  • CC (Cell Culture: Listed application)
$1,032.23 View price
  • 50 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN8128281
IL-10 Protein (AA 19-178) IL10 · Protein Human HEK-293F Cells
  • AcA (Activity Assay: Listed application)
  • CC (Cell Culture: Listed application)
$919.06 View price
  • 50 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN8128282
IL-10 Protein (AA 19-178) IL10 · Protein Mouse HEK-293F Cells
  • AcA (Activity Assay: Listed application)
  • CC (Cell Culture: Listed application)
$892.02 View price
  • 50 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN8128284
IL-10 Protein (AA 19-178) IL10 · Protein Rabbit HEK-293F Cells
  • AcA (Activity Assay: Listed application)
  • CC (Cell Culture: Listed application)
$910.04 View price
  • 50 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN8128285
IL-10 Protein (AA 19-178) (His tag) IL10 · Protein Cow HEK-293F Cells
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
$801.88 View price
  • 50 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN8128289
IL-10 Protein (AA 19-178) (His tag) IL10 · Protein Rabbit HEK-293F Cells
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
$771.83 View price
  • 50 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN8128283
IL-10 Protein (AA 19-178) IL10 · Protein Rat HEK-293F Cells
  • AcA (Activity Assay: Listed application)
  • CC (Cell Culture: Listed application)
$709.74 View price
  • 50 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN8128286
IL-10 Protein (AA 19-178) (His tag) IL10 · Protein Human HEK-293F Cells
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
$639.63 View price
  • 50 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN8128287
IL-10 Protein (AA 19-178) (His tag) IL10 · Protein Mouse HEK-293F Cells
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
$531.46 View price
  • 50 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN8128288
IL-10 Protein (AA 19-178) (His tag) IL10 · Protein Rat HEK-293F Cells
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
$817.90 View price
  • 50 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN8128290
IL-10 Protein (AA 19-178) (His tag,Fc Tag) IL10 · Protein Rabbit HEK-293F Cells
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
$776.84 View price
  • 50 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN8128291
IL-10 Protein (AA 20-181) IL10 · Protein Dog HEK-293F Cells
  • AcA (Activity Assay: Listed application)
  • CC (Cell Culture: Listed application)
$902.03 View price
  • 50 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN8128292
IL-10 Protein (AA 20-181) (His tag) IL10 · Protein Dog HEK-293F Cells
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
$801.88 View price
  • 50 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN8128293
IL-10 Protein (AA 22-175) IL10 · Protein Chicken HEK-293F Cells
  • AcA (Activity Assay: Listed application)
  • CC (Cell Culture: Listed application)
$880.00 View price
  • 50 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN8128294
IL-10 Protein (AA 22-175) (His tag) IL10 · Protein Chicken HEK-293F Cells
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
$679.69 View price
  • 50 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN8128295
IL-10 Protein (AA 23-180) (His tag) IL10 · Protein Zebrafish (Danio rerio) HEK-293F Cells
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
$729.77 View price
  • 50 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN7479378
IL-10 Protein (AA 20-177, full length) (His tag) IL10 · Protein Sheep Yeast
  • SDS (SDS-PAGE: Validation image available)
  • ELISA (ELISA: Listed application)
$972.20 View price
  • 100 μg
  • 1 mg
  • 20 μg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN7478907
IL-10 Protein (AA 19-178, full length) (His tag) IL10 · Protein Cow Yeast
  • SDS (SDS-PAGE: Validation image available)
  • ELISA (ELISA: Listed application)
$972.20 View price
  • 100 μg
  • 1 mg
  • 20 μg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN5712490
IL-10 Protein (AA 19-178) (GST tag) IL10 · Protein Human Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Validation image available)
$529.10 View price
  • 100 μg
  • 1 mg
  • 10 μg
  • 20 μg
  • 200 μg
  • 500 μg
Delivery in 11 to 12 Business Days Shipping to: United States
Protein
  • AcA (Activity Assay: Listed application)
  • CC (Cell Culture: Listed application)
Origin
Cow
Host
HEK-293F Cells
Protein Type
Recombinant
Purity
> 95 %
Biological Activity
Active
Catalog No. ABIN8128279
$1,002.18
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • AcA (Activity Assay: Listed application)
  • CC (Cell Culture: Listed application)
Origin
Horse
Host
HEK-293F Cells
Protein Type
Recombinant
Purity
> 95 %
Biological Activity
Active
Catalog No. ABIN8128280
$1,032.23
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • AcA (Activity Assay: Listed application)
  • CC (Cell Culture: Listed application)
Origin
Human
Host
HEK-293F Cells
Protein Type
Recombinant
Purity
> 97 %
Biological Activity
Active
Catalog No. ABIN8128281
$919.06
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • AcA (Activity Assay: Listed application)
  • CC (Cell Culture: Listed application)
Origin
Mouse
Host
HEK-293F Cells
Protein Type
Recombinant
Purity
> 97 %
Biological Activity
Active
Catalog No. ABIN8128282
$892.02
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • AcA (Activity Assay: Listed application)
  • CC (Cell Culture: Listed application)
Origin
Rabbit
Host
HEK-293F Cells
Protein Type
Recombinant
Purity
> 97 %
Biological Activity
Active
Catalog No. ABIN8128284
$910.04
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
Origin
Cow
Host
HEK-293F Cells
Protein Type
Recombinant
Purity
> 95 %
Catalog No. ABIN8128285
$801.88
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
Origin
Rabbit
Host
HEK-293F Cells
Protein Type
Recombinant
Purity
> 95 %
Catalog No. ABIN8128289
$771.83
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • AcA (Activity Assay: Listed application)
  • CC (Cell Culture: Listed application)
Origin
Rat
Host
HEK-293F Cells
Protein Type
Recombinant
Purity
> 90 %
Biological Activity
Active
Catalog No. ABIN8128283
$709.74
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
Origin
Human
Host
HEK-293F Cells
Protein Type
Recombinant
Purity
> 97 %
Catalog No. ABIN8128286
$639.63
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
Origin
Mouse
Host
HEK-293F Cells
Protein Type
Recombinant
Purity
> 97 %
Catalog No. ABIN8128287
$531.46
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
Origin
Rat
Host
HEK-293F Cells
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN8128288
$817.90
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
Origin
Rabbit
Host
HEK-293F Cells
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN8128290
$776.84
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • AcA (Activity Assay: Listed application)
  • CC (Cell Culture: Listed application)
Origin
Dog
Host
HEK-293F Cells
Protein Type
Recombinant
Purity
> 95 %
Biological Activity
Active
Catalog No. ABIN8128291
$902.03
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
Origin
Dog
Host
HEK-293F Cells
Protein Type
Recombinant
Purity
> 95 %
Catalog No. ABIN8128292
$801.88
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • AcA (Activity Assay: Listed application)
  • CC (Cell Culture: Listed application)
Origin
Chicken
Host
HEK-293F Cells
Protein Type
Recombinant
Purity
> 95 %
Biological Activity
Active
Catalog No. ABIN8128293
$880.00
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
Origin
Chicken
Host
HEK-293F Cells
Protein Type
Recombinant
Purity
> 95 %
Catalog No. ABIN8128294
$679.69
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
Origin
Zebrafish (Danio rerio)
Host
HEK-293F Cells
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN8128295
$729.77
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • SDS (SDS-PAGE: Validation image available)
  • ELISA (ELISA: Listed application)
Origin
Sheep
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN7479378
$972.20
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • SDS (SDS-PAGE: Validation image available)
  • ELISA (ELISA: Listed application)
Origin
Cow
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN7478907
$972.20
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • SDS (SDS-PAGE: Validation image available)
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
Greater than 90 % as determined by SDS-PAGE.
Catalog No. ABIN5712490
$529.10
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 12 Business Days

Latest Publications for our IL-10 Proteins

Phadnis-Moghe, Crawford, Kaminski: "Suppression of human B cell activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin involves altered regulation of B cell lymphoma-6." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 144, Issue 1, pp. 39-50, (2015) (PubMed).

Larson, Hübner, Torrero, Morris, Brankin, Swierczewski, Davies, Vonakis, Mitre: "Chronic helminth infection reduces basophil responsiveness in an IL-10-dependent manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 9, pp. 4188-99, (2012) (PubMed).

Yang, Hirose, Takahashi, Kawakatsu, Takaiwa: "Recombinant protein yield in rice seed is enhanced by specific suppression of endogenous seed proteins at the same deposit site." in: Plant biotechnology journal, Vol. 10, Issue 9, pp. 1035-45, (2012) (PubMed).

Del Galdo, Wermuth, Addya, Fortina, Jimenez et al.: "NF?B activation and stimulation of chemokine production in normal human macrophages by the gadolinium-based magnetic resonance contrast agent Omniscan: possible role in the pathogenesis of ..." in: Annals of the rheumatic diseases, Vol. 69, Issue 11, pp. 2024-33, (2010) (PubMed).

van der Vliet, Wang, Yue, Koon, Balk, Exley: "Circulating myeloid dendritic cells of advanced cancer patients result in reduced activation and a biased cytokine profile in invariant NKT cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 11, pp. 7287-93, (2008) (PubMed).

Prussin, Metcalfe: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, (1996) (PubMed).

Schlaak, Schmitt, Hüls, Meyer zum Büschenfelde, Fleischer: "A sensitive and specific bioassay for the detection of human interleukin-10." in: Journal of immunological methods, Vol. 168, Issue 1, pp. 49-54, (1994) (PubMed).

Feng, Tang, Chang, Wilson: "Molecular cloning of rat cytokine synthesis inhibitory factor (IL-10) cDNA and expression in spleen and macrophages." in: Biochemical and biophysical research communications, Vol. 192, Issue 2, pp. 452-8, (1993) (PubMed).

Howard, OGarra, Ishida, de Waal Malefyt, de Vries: "Biological properties of interleukin 10." in: Journal of clinical immunology, Vol. 12, Issue 4, pp. 239-47, (1992) (PubMed).

Vieira, de Waal-Malefyt, Dang, Johnson, Kastelein, Fiorentino, deVries, Roncarolo, Mosmann, Moore: "Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 4, pp. 1172-6, (1991) (PubMed).

Aliases for IL-10 Proteins

interleukin 10 (IL10) Proteins
interleukin 10 (Il10) Proteins
CSIF Proteins
GVHDS Proteins
IL-10 Proteins
Il-10 Proteins
IL10A Proteins
IL10X Proteins
TGIF Proteins
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