IL-18 Proteins

The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011].

Latest Publications for our IL-18 Proteins

Iyer, Grizotte-Lake, Duncan, Gordon, Palmer, Calvin, Zhong, Isoherranen, Vaishnava: "Epithelium intrinsic vitamin A signaling co-ordinates pathogen clearance in the gut via IL-18." in: PLoS pathogens, Vol. 16, Issue 4, pp. e1008360, (2020) (PubMed).

Moriwaki, Bertin, Gough, Chan: "A RIPK3-caspase 8 complex mediates atypical pro-IL-1β processing." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 4, pp. 1938-44, (2015) (PubMed).

Uzan, Poglio, Gerby, Wu, Gross, Armstrong, Calvo, Cahu, Deswarte, Dumont, Passaro, Besnard-Guérin, Leblanc, Baruchel, Landman-Parker, Ballerini, Baud, Ghysdael, Baleydier, Porteu, Pflumio: "Interleukin-18 produced by bone marrow-derived stromal cells supports T-cell acute leukaemia progression." in: EMBO molecular medicine, Vol. 6, Issue 6, pp. 821-34, (2014) (PubMed).

Kahlenberg, Carmona-Rivera, Smith, Kaplan: "Neutrophil extracellular trap-associated protein activation of the NLRP3 inflammasome is enhanced in lupus macrophages." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 3, pp. 1217-26, (2013) (PubMed).

Kahlenberg, Thacker, Berthier, Cohen, Kretzler, Kaplan: "Inflammasome activation of IL-18 results in endothelial progenitor cell dysfunction in systemic lupus erythematosus." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 11, pp. 6143-56, (2011) (PubMed).

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

Ushio, Namba, Okura, Hattori, Nukada, Akita, Tanabe, Konishi, Micallef, Fujii, Torigoe, Tanimoto, Fukuda, Ikeda, Okamura, Kurimoto: "Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 156, Issue 11, pp. 4274-9, (1996) (PubMed).

Aliases for IL-18 Proteins

interleukin 18 (Il18) Proteins
interleukin 18 (IL18) Proteins
ChIL-18 Proteins
Igif Proteins
IGIF Proteins
IL-1g Proteins
Il-18 Proteins
IL-18 Proteins
IL1F4 Proteins
IL18 Proteins

IL-18 Proteins

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Latest Publications for our IL-18 Proteins

Aliases for IL-18 Proteins

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